Results 201 to 210 of about 5,727,939 (389)

CPL‐Diff: A Diffusion Model for De Novo Design of Functional Peptide Sequences with Fixed Length

open access: yesAdvanced Science, EarlyView.
This study presents a diffusion model for generating functional peptide sequence lengths using mask control. The model can generate antimicrobial, antifungal, and antiviral peptides with specific lengths on demand. The model learns the structure of peptides better and generates peptides with better physicochemical properties, and the model has good ...
Zhenjie Luo   +5 more
wiley   +1 more source

Patterns of community violence exposure among urban adolescents and their associations with adjustment

open access: yesAmerican Journal of Community Psychology, Volume 70, Issue 3-4, Page 265-277, December 2022., 2022
Abstract Community violence exposure is prevalent among urban and marginalized adolescents. Although there is strong evidence that community violence exposure is associated with negative consequences, prior studies and theories suggest that these associations may differ as a function of specific characteristics of exposure.
Sarah K. Pittman, Albert D. Farrell
wiley   +1 more source

An Agrin–YAP/TAZ Rigidity Sensing Module Drives EGFR‐Addicted Lung Tumorigenesis

open access: yesAdvanced Science, EarlyView.
The study identifies agrin‐EGFR mechanotransduction as a critical driver of lung adenocarcinoma which enhances EGFR signaling through an integrin‐FAK‐actomyosin dependent positive feedback on YAP/TAZ ‐TEAD in response to matrix stiffness. Targeting this oncogenic loop through combinatorial treatments inhibits lung cancer due to agrin impairment.
Reza Bayat Mokhtari   +20 more
wiley   +1 more source

The Achieved Capabilities Questionnaire for Community Mental Health (ACQ‐CMH): A consumer‐based measure for the evaluation of community mental health interventions

open access: yesAmerican Journal of Community Psychology, Volume 70, Issue 3-4, Page 327-339, December 2022., 2022
Abstract The capabilities approach offers a multidimensional, ecological, and agent‐centered framework that may inspire models of intervention and evaluation. A growing number of measures grounded on the capabilities approach for outcome measurement are appearing.
Beatrice Sacchetto   +2 more
wiley   +1 more source

Impact of Obesity in Critical Illness

open access: yesChest, 2021
Michael R. Anderson, M. Shashaty
semanticscholar   +1 more source

Neural Patterns of Social Pain in the Brain‐Wide Representations Across Social Contexts

open access: yesAdvanced Science, EarlyView.
Empathy arises from both physiological and social pain, yet their shared and context‐specific neural mechanisms remain unclear. Combining fMRI and multivariate pattern analysis, this study decodes overlapping empathy networks and distinct representations for social exclusion versus separation.
Xiaodong Zhang   +11 more
wiley   +1 more source

Metal‐Organic Framework‐Based Tribovoltaic Textile for Human Body Signal Monitoring

open access: yesAdvanced Science, EarlyView.
A metal‐organic framework‐based tribovoltaic textile (TVT) is developed using copper‐benzenehexathiol (Cu‐BHT) as a novel p‐type semiconductor. The Cu‐BHT TVT consistently produces pure DC output due to self‐rectification and exhibits excellent flexibility and stability.
Yuanlong Li   +3 more
wiley   +1 more source

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