Results 61 to 70 of about 6,679,818 (388)

Protocol for a longitudinal qualitative study: survivors of childhood critical illness exploring long-term psychosocial well-being and needs–The SCETCH Project [PDF]

open access: yes, 2014
Life-threatening critical illness affects over a quarter of a million children and adolescents (0-18 years old) annually in the USA and the UK. Death from critical illness is rare; however, survivors and their families can be exposed to a complex array ...
Hemingway, Pippa   +2 more
core   +4 more sources

Nonthyroidal illness in critically ill children [PDF]

open access: yesCurrent Opinion in Endocrinology, Diabetes & Obesity, 2019
Purpose of review This review summarizes recent literature on nonthyroidal illness syndrome (NTI) and outcome of pediatric critical illness, to provide insight in pathophysiology and therapeutic implications. Recent findings NTI is typically characterized by lowered triiodothyronine
Jacobs, An   +2 more
openaire   +3 more sources

Reduced Cortisol Metabolism during Critical Illness [PDF]

open access: yes, 2013
Critical illness is often accompanied by hypercortisolemia, which has been attributed to stress-induced activation of the hypothalamic-pituitary-adrenal axis. However, low corticotropin levels have also been reported in critically ill patients, which may
Andrew, Ruth   +13 more
core   +1 more source

Model-based Prediction of Critical Illness in Hospitalized Patients with COVID-19

open access: yesRadiology, 2020
Background The prognosis of hospitalized patients with severe coronavirus disease 2019 (COVID-19) is difficult to predict, while the capacity of intensive care units (ICUs) is a limiting factor during the peak of the pandemic and generally dependent on a
S. Schalekamp   +11 more
semanticscholar   +1 more source

The microbiome and the immune system in critical illness.

open access: yesCurrent Opinion in Critical Care, 2021
PURPOSE OF REVIEW Although the gut microbiome plays a crucial role in the maintenance of health, it is hypothesized to drive morbidity and mortality in critically ill patients.
Ashley A Miniet   +2 more
semanticscholar   +1 more source

Dealing with missing delirium assessments in prospective clinical studies of the critically ill: a simulation study and reanalysis of two delirium studies

open access: yesBMC Medical Research Methodology, 2021
Background In longitudinal critical care studies, researchers may be interested in summarizing an exposure over time and evaluating its association with a long-term outcome. For example, the number of days a patient has delirium (i.e., brain dysfunction)
Rameela Raman   +6 more
doaj   +1 more source

Metabolic aspects of muscle wasting during critical illness

open access: yesCurrent opinion in clinical nutrition and metabolic care, 2020
Purpose of review Skeletal muscle wasting during critical illness is the result of disturbed metabolism. No proven effective interventions targeting skeletal muscle mass and function during critical illness currently exist.
R. V. van Gassel   +2 more
semanticscholar   +1 more source

Rehabilitation after critical illness

open access: yesBritish medical journal, 2021
Essential for all intensive care patients, not just people recovering from covid ...
Catherine White   +2 more
semanticscholar   +1 more source

Rehabilitation After Critical Illness in People With COVID-19 Infection

open access: yesAmerican Journal of Physical Medicine & Rehabilitation, 2020
The current COVID-19 pandemic will place enormous pressure on healthcare systems around the world. Large numbers of people are predicted to become critically ill with acute respiratory distress syndrome and will require management in intensive care units.
Robert Simpson, Larry Robinson
semanticscholar   +1 more source

Natural Product Alantolactone Targeting AKR1C1 Suppresses Cell Proliferation and Metastasis in Non-Small-Cell Lung Cancer

open access: yesFrontiers in Pharmacology, 2022
Non-small-cell lung cancer (NSCLC) is one of the leading causes of cancer-related deaths, characterized by high invasion and metastasis. Aldo-keto reductase family 1 member C1 (AKR1C1) plays an important role in cancer cell proliferation and metastasis ...
Zhiwen Fu   +15 more
doaj   +1 more source

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