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Protocol for a longitudinal qualitative study: survivors of childhood critical illness exploring long-term psychosocial well-being and needs–The SCETCH Project [PDF]
, 2014 Life-threatening critical illness affects over a quarter of a million children and adolescents (0-18 years old) annually in the USA and the UK. Death from critical illness is rare; however, survivors and their families can be exposed to a complex array ...
Hemingway, Pippa +2 more
core +3 more sources
Model-based Prediction of Critical Illness in Hospitalized Patients with COVID-19
Radiology, 2020 Background The prognosis of hospitalized patients with severe coronavirus disease 2019 (COVID-19) is difficult to predict, while the capacity of intensive care units (ICUs) is a limiting factor during the peak of the pandemic and generally dependent on a
S. Schalekamp +11 more
semanticscholar +1 more source
BMC Medical Research Methodology, 2021 Background In longitudinal critical care studies, researchers may be interested in summarizing an exposure over time and evaluating its association with a long-term outcome. For example, the number of days a patient has delirium (i.e., brain dysfunction)
Rameela Raman +6 more
doaj +1 more source
Metabolic aspects of muscle wasting during critical illness
Current opinion in clinical nutrition and metabolic care, 2020 Purpose of review Skeletal muscle wasting during critical illness is the result of disturbed metabolism. No proven effective interventions targeting skeletal muscle mass and function during critical illness currently exist.
R. V. van Gassel +2 more
semanticscholar +1 more source
Reduced Cortisol Metabolism during Critical Illness [PDF]
, 2013 Critical illness is often accompanied by hypercortisolemia, which has been attributed to stress-induced activation of the hypothalamic-pituitary-adrenal axis. However, low corticotropin levels have also been reported in critically ill patients, which may
Andrew, Ruth +13 more
core +1 more source
Rehabilitation After Critical Illness in People With COVID-19 Infection
American Journal of Physical Medicine & Rehabilitation, 2020 The current COVID-19 pandemic will place enormous pressure on healthcare systems around the world. Large numbers of people are predicted to become critically ill with acute respiratory distress syndrome and will require management in intensive care units.
Robert Simpson, Larry Robinson
semanticscholar +1 more source
Explainable artificial intelligence model to predict acute critical illness from electronic health records [PDF]
Nature Communications, 2019 Acute critical illness is often preceded by deterioration of routinely measured clinical parameters, e.g., blood pressure and heart rate. Early clinical prediction is typically based on manually calculated screening metrics that simply weigh these ...
S. Lauritsen +7 more
semanticscholar +1 more source
Frontiers in Pharmacology, 2022 Non-small-cell lung cancer (NSCLC) is one of the leading causes of cancer-related deaths, characterized by high invasion and metastasis. Aldo-keto reductase family 1 member C1 (AKR1C1) plays an important role in cancer cell proliferation and metastasis ...
Zhiwen Fu +15 more
doaj +1 more source
Association of Hypoactive and Hyperactive Delirium With Cognitive Function After Critical Illness
Critical Care Medicine, 2020 Supplemental Digital Content is available in the text. Objectives: Delirium, a heterogenous syndrome, is associated with worse long-term cognition after critical illness.
C. Hayhurst +13 more
semanticscholar +1 more source
Critical Care, 2020 Background COVID-19 can course with respiratory and extrapulmonary disease. SARS-CoV-2 RNA is detected in respiratory samples but also in blood, stool and urine. Severe COVID-19 is characterized by a dysregulated host response to this virus.
J. Bermejo-Martín +65 more
semanticscholar +1 more source