Results 101 to 110 of about 38,429 (312)

Impact of Antihypertensive Treatment on Outcomes of Adjuvant Bevacizumab for Ovarian Cancer (IATRO), Results from a Nationwide Emulated Clinical Trial

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Antiangiogenic therapy with bevacizumab improves outcomes in ovarian cancer but induces hypertension, leading to major adverse cardiovascular events (MACE). While calcium channel blockers (CCBs) and angiotensin‐converting enzyme inhibitors (ACEi) are recommended for managing bevacizumab‐associated hypertension, their impacts on cancer progression and ...
Floriane Jochum   +10 more
wiley   +1 more source

Pathogenesis and potential therapeutic targets of trichorhinophalangeal syndrome; lessons obtained from animal studies

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Trichorhinophalangeal syndrome (TRPS) is a rare genetic disease inherited in an autosomal dominant manner. It occurs in 1 in 100,000 people globally and is caused by several types of mutations of the TRPS1 gene. Since the first human patient was reported in 1966, typical and atypical pathologies, disease courses, and treatment case ...
Naoya Saeki   +6 more
wiley   +1 more source

Skin perfusion pressure measurement is valuable in the diagnosis of critical limb ischemia

open access: bronze, 1997
John J. Castronuovo   +3 more
openalex   +1 more source

Prognostic impact of SCAI shock severity classes in AMI‐related cardiogenic shock: A sub‐study of the ECLS‐SHOCK Trial

open access: yesESC Heart Failure, EarlyView.
Patients with AMI‐CS (lactate >3 mmol/L) enrolled in the multicentre, randomized ECLS‐SHOCK trial were included. From a total of 417 patients, 51.6% (n = 215), 13.4% (n = 56) and 35.0% (n = 146) presented in SCAI Stages C, D and E, respectively. SCAI stages were associated with the risk of 30 day all‐cause mortality, with rates of renal replacement ...
Janine Pöss   +13 more
wiley   +1 more source

Angiogenic Gene Therapy for Experimental Critical Limb Ischemia [PDF]

open access: bronze, 2002
Ichiro Masaki   +11 more
openalex   +1 more source

Impact of comorbidity burden on outcome in patients with cardiogenic shock: A Cardiogenic Shock Working Group analysis

open access: yesEuropean Journal of Heart Failure, EarlyView.
Impact of comorbidity burden on outcome in patients with cardiogenic shock. AMI, acute myocardial infarction; CAD, coronary artery disease; CI, confidence interval; CKD, chronic kidney disease; COMRI‐CS; Comorbidity Risk Index for Cardiogenic Shock; COPD, chronic obstructive pulmonary disease; CS, cardiogenic shock; CSWG, Cardiogenic Shock Working ...
Jonas Sundermeyer   +52 more
wiley   +1 more source

Red blood cell endothelial nitric oxide synthase: A major player in regulating cardiovascular health

open access: yesBritish Journal of Pharmacology, EarlyView., 2023
Abstract Red blood cells (RBCs) have traditionally been seen as simple carriers of gases and nutrients in the body. One important non‐canonical function of RBCs in the cardiovascular system is the regulation of nitric oxide (NO) metabolism. It has been shown that RBCs can scavenge NO, transport NO metabolites and produce NO in hypoxic conditions ...
Anthea LoBue   +7 more
wiley   +1 more source

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