Results 21 to 30 of about 129,036 (402)

Cell Therapy for Critical Limb Ischemia: Advantages, Limitations, and New Perspectives for Treatment of Patients with Critical Diabetic Vasculopathy

Current Diabetes Reports, 2021
Purpose of Review To provide a highlight of the current state of cell therapy for the treatment of critical limb ischemia in patients with diabetes. Recent Findings The global incidence of diabetes is constantly growing with consequent challenges for ...
Y. Gu, A. Rampin, V. Alvino, G. Spinetti, P. Madeddu   +4 more
semanticscholar   +1 more source

Modern methods of stimulation of angiogenesis in patients with critical limb ischemia (review)

Journal of Education, Health and Sport, 2017
The term "critical ischemia of extremities" (critical limb ischemia) was first introduced by P.R.F. Bell in 1982 to refer to a group of diseases accompanied by pain in the legs at rest, trophic ulcers and distal necroses of the lower limbs.
I. A. Kryvoruchko, S. K.-T. Goni, M. S. Antonova, M. A. Sykal, U. M. Voronaja, M. A. Alexandrov, N. V. Lola   +6 more
doaj   +3 more sources

Crossing complex infrapopliteal lesions utilizing a front-end cutting technique: A report of two cases with a novel rotational atherectomy device

SAGE Open Medical Case Reports, 2023
Critical limb ischemia represents the most severe stage of peripheral vascular disease and patients often present with complex, calcified infrapopliteal lesions.
Siddhartha Rao, Anton Hnatov, Trisha Tarra, Amber Amparo, Mallika Bhargava   +4 more
doaj   +1 more source

Critical Limb Ischemia [PDF]

Journal of the American College of Cardiology, 2016
Critical limb ischemia (CLI), the most advanced form of peripheral artery disease, is associated with significant morbidity, mortality, and health care resource utilization. It is also associated with physical, as well as psychosocial, consequences such as amputation and depression. Importantly, after a major amputation, patients are at heightened risk
Marc Bosiers, Peter Schneider
openaire   +5 more sources

Combination of Antioxidant Enzyme Overexpression and N‐Acetylcysteine Treatment Enhances the Survival of Bone Marrow Mesenchymal Stromal Cells in Ischemic Limb in Mice With Type 2 Diabetes

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Therapy with mesenchymal stem cells remains a promising but challenging approach to critical limb ischemia in diabetes because of the dismal cell survival.
Qiang Zhu, Hong Hao, Huifang Xu, Yosef Fichman, Yuqi Cui, Chunlin Yang, Meifang Wang, Ron Mittler, Michael A. Hill, Peter J. Cowan, Guangsen Zhang, Xiaoming He, Shenghua Zhou, Zhenguo Liu   +13 more
doaj   +1 more source

Endothelial Progenitor Cells May Be Related to Major Amputation after Angioplasty in Patients with Critical Limb Ischemia

Cells, 2023
Background: Critical limb ischemia represents an advanced stage of peripheral arterial disease. Angioplasty improves blood flow to the limb; however, some patients progress irreversibly to lower limb amputation.
Daniel Santillán-Cortez, Eduardo Vera-Gómez, Alejandro Hernández-Patricio, Atzín Suá Ruíz-Hernández, Juan Ariel Gutiérrez-Buendía, Karen De la Vega-Moreno, Yasser Alberto Rizo-García, Oscar Antonio Loman-Zuñiga, Ignacio Escotto-Sánchez, Juan Miguel Rodríguez-Trejo, Mario Antonio Téllez-González, Christian Gabriel Toledo-Lozano, Tania Ortega-Rosas, Silvia García, Paul Mondragón-Terán, Juan Antonio Suárez-Cuenca   +15 more
doaj   +1 more source

Limb salvage following below-the-ankle angioplasty in critical limb ischemia

Indian Journal of Vascular and Endovascular Surgery, 2020
Aim: The aim was to report limb salvage following below-the-ankle (BTA) angioplasty as an adjunct to proximal angioplasty in patients with critical limb ischemia (CLI).
B Nishan, K Siva Krishna, V Vishal Hudgi, V P Ahsan, Vivek Anand   +4 more
doaj   +1 more source

Endovascular treatment of critical lower limb ischemia caused by giant cell arteritis

Journal of Vascular Surgery Cases and Innovative Techniques, 2019
Giant cell arteritis (GCA) is a well-known cause of cranial vasculitis often presenting with headache and jaw claudication. Here we report the case of a woman suffering GCA who presented with critical lower limb ischemia.
Rohan H.P. McLachlan, MD, BMS, Andrew F. Lennox, MBBS, MSc, FRACS, Ramon L. Varcoe, MBBS, MS, FRACS, Shannon D. Thomas, BSc Med Hons, MBBS, FRACS   +3 more
doaj   +1 more source

Mesenchymal stem cells to augment therapeutic angiogenesis in hind-limb ischemia models: how important is their source? [PDF]

, 2013
Murine models of hind-limb ischemia are frequently used to assess interventions aimed at improving therapeutic angiogenesis in critical limb ischemia. Much of the current focus of angiogenesis lies with mesenchymal stem cells (MSCs).
Duffy, Garry P, Herron, Caroline C
core   +1 more source

Sympathectomy and Neuromodulation in the Treatment of Critical Lower Limb Ischemia

Неотложная медицинская помощь, 2022
INTRODUCTION Critical lower limb ischemia is a widespread disease that occurs due to atherosclerotic lesions of the arteries with progressive narrowing of their lumen.
A. V. Yarikov, V. A. Leonov, M. V. Shpagin, O. A. Perlmutter, A. P. Fraerman, А. S. Mukhin, A. E. Kletskin, V. G. Lyutikov, D. G. Kuzminykh   +8 more
doaj   +1 more source