Results 11 to 20 of about 10,215,756 (277)

Assessment of critical material attributes of polyethylene oxide for formulation of prolonged-release tablets

open access: yesDrug Development and Industrial Pharmacy, 2019
Physicochemical evaluation of polyethylene oxide (PEO) polymers with various molecular weights was performed at molecular (polymeric dispersion) and bulk level (powders, polymeric films, and tablets) with the aim of specifying polymer critical material attributes with the main contribution to drug release from prolonged-release tablets (PRTs). For this
Petra, Draksler   +4 more
openaire   +3 more sources

The Internationalisation of UK Higher Education: From ‘technical observance’ to ‘relational participation’, the road to CAPRI… [PDF]

open access: yes, 2009
This article reflects on a review of the literature on the internationalisation of UK higher education (HE) commissioned by the Higher Education Academy (HEA) in 2006.
Caruana, V
core   +8 more sources

QbD enabled Process Variable Study to Develop Sustained Release Chitosan-Alginate Embedded Delivery System for Improved Patient Compliance

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2022
The current investigation entail systematic Quality by Design (QbD)-enabled approach for the development of Sustained released embedded drug delivery systems of L-Arginine employing ionic gelation technique to attain improved patient compliance.
Vijay Sharma, Lalit Singh, Navneet Verma
doaj   +1 more source

Critical material attributes during continuous twin-screw wet granulation

open access: yes
Twin-screw wet granulation (TSWG) has evolved in recent years into a mature, effective, and widely adopted technique. This has been accompanied by an enhanced understanding of the process through the identification of critical process parameters (CPPs ...
Vanhoorne, Valérie   +2 more
openaire   +2 more sources

Using a Material Library to Understand the Change of Tabletability by High Shear Wet Granulation

open access: yesPharmaceutics, 2022
Understanding the tabletability change of materials after granulation is critical for the formulation and process design in tablet development. In this paper, a material library consisting of 30 pharmaceutical materials was used to summarize the pattern ...
Yawen Wang   +6 more
doaj   +1 more source

Application of Quality-by-Design Approach to Justify the Composition and Technology of Two-component Suppositories

open access: yesРазработка и регистрация лекарственных средств, 2022
Introduction. One of the modern remedies used to treat vaginal infections are suppositories "Depantol", which have an antiseptic, regenerating effect due to the combination of chlorhexidine and dexpanthenol.
I. E. Smekhova   +4 more
doaj   +1 more source

SeDeM as a Tool to Validate Drug Substance Manufacturing Processes and Assess Scalability and Suitability for Direct Compression: Supplier Screening

open access: yesPharmaceutics, 2023
During the development of an oral solid form of a drug substance, a thorough understanding of the critical material attributes is necessary, as the physical properties of the active pharmaceutical ingredient (API) can profoundly influence the drug ...
Alba Figuera-Figuera   +5 more
doaj   +1 more source

An investigation into the material efficiency practices of UK manufacturers [PDF]

open access: yes, 2009
This thesis examines the Material Efficiency practices of manufacturing companies in the UK. The study was motivated by the increasing attention given by literature to sustainable strategies in general, with less attention being given to material ...
Abdul Rashid, Salwa Hanim
core   +7 more sources

Quality by design prospects of pharmaceuticals application of double emulsion method for PLGA loaded nanoparticles

open access: yesSN Applied Sciences, 2021
QbD approach empowers the pharma researchers to minimize the number of experimental trials and time. It helps identify the significant, influential factors such as critical material attributes, critical formulation variables, and critical process ...
Dhananjay Panigrahi   +3 more
doaj   +1 more source

Quality by Design: Development of the Quality Target Product Profile (QTPP) for Semisolid Topical Products

open access: yesPharmaceutics, 2020
In recent years, the “quality by design” (QbD) approach has been used for developing pharmaceutical formulations. This is particularly important for complex dosage forms such as topical semisolid products.
Sarika Namjoshi   +4 more
doaj   +1 more source

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