Results 31 to 40 of about 10,215,756 (277)

Soft Gelatine Capsules- Critical Quality Attributes of Chosen Excipients and Capsules Parameters Following the Quality by Design Concept [PDF]

Acta Poloniae Pharmaceutica, 2023
Soft gel capsules are a common form of medicine and food supplements. Quality, productivity and manufacturing time is crucial for producers during their development and industrial operations.
Barbara Owczarek, Edyta Łukowska-Chojnacka   +1 more
doaj   +1 more source

Quantifying spatiotemporal dynamics of urban building and material metabolism by combining a random forest model and GIS-based material flow analysis

Frontiers in Earth Science, 2022
Understanding building metabolism is critical for guiding urban resource management and addressing challenges in urban sustainable development.
Ting Mao, Ting Mao, Ting Mao, Yupeng Liu, Yupeng Liu, Yupeng Liu, Wei-Qiang Chen, Wei-Qiang Chen, Wei-Qiang Chen, Nan Li, Nan Li, Nan Li, Nan Dong, Yao Shi   +13 more
doaj   +1 more source

PRELIMINARY STUDY OF INSULIN DRY POWDER FORMULATION: CRITICAL PROCESS PARAMETERS ON SPRAY-FREEZE-DRYING AND CRITICAL MATERIAL ATTRIBUTE OF TREHALOSE AND INULIN AS STABILIZER

International Journal of Applied Pharmaceutics, 2021
Objective: The aim of this study was to obtain recommendations about critical process parameters (CPP) and optimal ratio of trehalose and inulin as critical material attribute (CMA) on insulin dry powder formulation with spray-freeze-drying (SFD) method.
CYNTHIA MARISCA MUNTU, SILVIA SURINI, CHRISTINA AVANTI, null HAYUN, WOUTER HINRICHS   +4 more
openaire   +2 more sources

The development of an herbal material quality control strategy considering the effects of manufacturing processes

Chinese Medicine, 2019
Background Quality by design (QbD) is an advanced drug quality control concept that has been gradually implemented in the optimization of manufacturing processes of Chinese medicines.
Jingjing Pan, Siyuan He, Jiayao Zheng, Jingyuan Shao, Ning Li, Yunqi Gong, Xingchu Gong   +6 more
doaj   +1 more source

Risk-Based Approach for Defining Retest Dates for Active Pharmaceutical Ingredients and Excipients

Pharmaceuticals
Drug substances and excipients must be stored in recommended storage conditions and should comply with their specifications during the retest period for their use in the manufacture of drug products.
Naseem A. Charoo, Omotayo Akanji, Ziyaur Rahman, Aqeel A. Khan, Aqal Badshah   +4 more
doaj   +1 more source

Quality by Design Approach for the Development of Liposome Carrying Ghrelin for Intranasal Administration

Pharmaceutics, 2021
The therapeutic use of peptides has increasingly recognized in the development of new therapies. However, the susceptible enzymatic cleavage is a barrier that needs to overcome.
Cecília de Barros, Norberto Aranha, Patrícia Severino, Eliana B. Souto, Aleksandra Zielińska, André Lopes, Alessandra Rios, Fernando Batain, Kessi Crescencio, Marco Chaud, Thais Alves   +10 more
doaj   +1 more source

Bridging Material Variability and Tablet Performance: Optimization of Direct Compression Using Tensile Strength–Ejection Stress Mapping

Pharmaceutics
Objectives: The current study presents a sequential strategy for the development of directly compressible powder formulations relying on Design of Experiments (DoE) and Compactibility-Ejection stress plots.
Tibor Casian, Sonia Iurian, Alexandru Gâvan, Oana Negoi, Damaris Marusca, Adriana Marina, Maria Suciu, Dana Muntean, Alina Porfire, Anca Lucia Pop, Simona Crișan, Dumitru Cauni, Ioan Tomuță   +12 more
doaj   +1 more source

Oral Soluble Films: Attributes of the Polymeric Material and Critical Process Parameters for Designing Good Quality Films

Current Applied Polymer Science, 2020
Background::Soluble films prepared using polymeric matrices have gained prominence in drug delivery because of its multifarious merits. They are emerging as a momentous technology for designing precision medicines using printing technology, wherein the drugs, proteins/peptides and hormones in printing ink solution can be printed on placebo films ...
Suhani Sinha, Rohit Dutt
openaire   +1 more source

Weakly Supervised Learning of Objects, Attributes and their Associations [PDF]

, 2014
. When humans describe images they tend to use combinations of nouns and adjectives, corresponding to objects and their associated attributes respectively.
Zhiyuan Shi, Yongxin Yang, Yang, Yongxin, Tao Xiang, Timothy M. Hospedales, Yang, Y, Hospedales, Timothy M, Xiang, Tao, Shi, Z, Xiang, T, Shi, Zhiyuan, Hospedales, TM   +11 more
core   +1 more source

Handling continuous attributes in ant colony classification algorithms [PDF]

, 2009
Most real-world classification problems involve continuous (real-valued) attributes, as well as, nominal (discrete) attributes. The majority of Ant Colony Optimisation (ACO) classification algorithms have the limitation of only being able to cope with ...
Otero, Fernando E.B., Colin G. Johnson, Johnson, Colin G., Alex A. Freitas, Freitas, Alex A., Fernando E. B. Otero   +5 more
core   +1 more source