Results 51 to 60 of about 10,215,756 (277)
International Journal of Pharmaceutics: XThe contributions of fine excipient materials to drug dispersibility from carrier-based dry powder inhalation (DPI) formulations are well recognized, although they are not completely understood.
Mustafa M.A. Elsayed +7 more
doaj +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Machine learning-driven exosome-mimetic lipid nanoparticles for tumor-specific targeting
Nano ConvergenceExosome-mimetic lipid nanoparticles (ENPs) are a promising alternative to PEGylated lipid nanoparticles (LNPs) for targeted cancer therapy, offering improved biocompatibility and reduced immune clearance.
Seongmin Ha +10 more
doaj +1 more source
International Journal of Applied Pharmaceutics, 2019 Objective: The current work highlights the use of the Quality by Design (QbD) for optimization of Nanocellulose (NC) production from corn husk by two techniques, namely, Acid hydrolysis (AH) and High pressure homogenization (HPH). Methods: Characterization of NC involved Fourier transform infrared spectroscopy (FTIR), thermo gravimetric analysis (TGA),
ROSHNI VORA, Yamini Shah
openaire +2 more sources
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Assessing Cost-Effective Materials for Multi-Functional Crutches: an Integrated MCDM Framework [PDF]
Archives of Metallurgy and MaterialsMaterial selection significantly impacts crutch performance and durability, posing challenges due to various criteria and complex decision-making in engineering design.
M. Joshi
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Two-dimensional material membranes for critical separations
, 2020 Separation technology is of great importance to the chemical industries which involve many steps of purification. Compared to the traditional thermal-based purification processes such as evaporation and distillation, membrane technology has attracted ...
Lu, Xiaoquan +5 more
core +1 more source