Results 71 to 80 of about 10,215,756 (277)
Quality Risk Management of Compliant Excipients
Raw material compliance and GMP do not eliminate variability. Quality by Design should minimize the risk that raw material variability will adversely affect the finished product Critical Quality Attributes.
Brian Carlin
doaj
The management of wounds primarily revolves around pain relief, effective infection control and the promotion of tissue regeneration to prevent complications like chronic skin wounds.
María Florencia Sanchez +3 more
doaj +1 more source
both play an important role in facilitating a higher level of process understanding, creating opportunities for root cause investigation, and developing control strategies for pharmaceutical products. To the best of our knowledge, this is the first time that MVDA and ANN were used to process such a broad range of data for the evaluation and ...
openaire +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Quality Risk Management of Compliant Excipients [PDF]
Raw material compliance and GMP do not eliminate variability. Quality by Design should minimize the risk that raw material variability will adversely affect the finished product Critical Quality Attributes.
Brian Carlin
doaj
Size-effect in microwave processing of engineering materials - A review
The size of material units is especially critical in manufacturing processes where thermal energy interacts with the material. The microwave energy is widely used to process the materials in industries such as food processing, chemical, manufacturing ...
Dhirendra N. Gamit, Mahesh K. Chudasama
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Daqu serves as a pivotal fermentation starter in Baijiu and vinegar production, driving complex microbial interactions that critically shape its physicochemical properties and sensory qualities.
Yong Yang +6 more
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
SEISMIC RESPONSE CHARACTERISTICS OF THE COAL SEAM IN THE KASHMIR BASIN BY USING MULTI-ATTRIBUTE FUSION TECHNOLOGY [PDF]
The increasing demand for efficient and sustainable coal extraction emphasizes the critical need for accurately characterizing coal seams. This study explores the utilization of multi-attribute seismic fusion technology to analyze the seismic response of
Ehtisham Mehmood, Haishen Lu
doaj +1 more source

