Results 231 to 240 of about 457,166 (295)

Next generation biobanking ontology: introducing-omics contextual data to biobanking ontology. [PDF]

Bioinform Adv
Alghamdi D, Dooley DM, Samman M, AlFaiz A, Hsiao WWL.   +4 more
europepmc   +1 more source

CD168 Identifies Proliferating Pancreatic Islet Cells in Murine and Human

Advanced Science, EarlyView.
This study identifies CD168 as a conserved surface marker for proliferating β‐cells in mouse, human islets, and pancreatic islet tumors. CD168⁺ cells show high proliferation and low insulin expression. CD168+ cells form mostly uni‐β lineage clones, and some of the clones are multi‐lineage.
Shubo Yuan, Jiafu Li, Min Shao, Haili Bao, Ajun Geng, Jialin Yang, Yu Tao, Xinyi Chen, Tianxiong Xiao, Chunye Liu, Zhiyao Xie, Wenqian Song, Qing Cissy Yu, Hongxing Fu, Xu Han, Taochen He, Wenquan Wang, Jianfeng Chen, Sheng Yan, Shaohua Song, Liang Liu, Yi Arial Zeng   +21 more
wiley   +1 more source

Semantic web ontology for structured knowledge representation and clinical decision support in eye diseases. [PDF]

Sci Rep
Anjum F, Maqbool F, Razzaq MS, Shehzad HMF, Ali S, Shah D, Tahir M, Ilyas M.   +7 more
europepmc   +1 more source

A Hydrodynamic Bioreactor for High‐Yield Production of Extracellular Vesicles from Stem Cell Spheroids with Defined Cargo Profiling

Advanced Science, EarlyView.
This study harnesses hydrodynamic flows to generate, confine and stimulate stem cell spheroids, enabling the large‐scale production of extracellular vesicles (EVs). This innovative method not only streamlines spheroid formation and subsequent EV release in a single, integrated process, but also ensures the generation of EVs with enhanced biological ...
Solène Lenoir, Elliot Thouvenot, Giacomo Gropplero, Léonie Dec, Damarys Loew, Clotilde Théry, Jose E Perez, Claire Wilhelm   +7 more
wiley   +1 more source

Single-cell analysis of B cell dysregulation in pediatric sepsis stratified by disease severity. [PDF]

Sci Rep
Alhamdan F, Gianoli S, Yuki K, Koutsogiannaki S.   +3 more
europepmc   +1 more source

Targeting Itga8 Mitigates Neurogenic Bladder Fibrosis Driven by Trem2⁺ Macrophage‐Derived Fn1 via FAK/RhoA/ROCK Signaling

Advanced Science, EarlyView.
Normal bladders exhibit quiescent fibroblasts/macrophages, whereas neurogenic bladders show acute‐phase Itga8⁺ fibroblast expansion driven by Trem2⁺ macrophage‐secreted Fn1, which activates FAK/RhoA/ROCK signaling, promotes cytoskeletal remodeling, and upregulates pro‐fibrotic genes.
Jiaxin Wang, Siyuan Wang, Lida Ren, Xinqi Liu, Lei Zhang, Peng Hu, Wenchao Xu, Shuaixiang Zheng, Jihong Liu, Qing Ling   +9 more
wiley   +1 more source

The Nature of Knowledge and Epistemic Interests of Radiography Science-An Analysis of Doctoral Dissertations Using Critical Normative Epistemology Framework. [PDF]

Scand J Caring Sci
Sanna T, Helena LK, Mervi S, Eija M.
europepmc   +1 more source

A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells

Advanced Science, EarlyView.
An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet, Sara Pugliese, Jordi Bruna, Daniel Ruiz‐Molina, Salvio Suárez‐García, Victor J. Yuste   +5 more
wiley   +1 more source

Functional proteomic analysis reveals <i>mglB</i>-mediated meropenem resistance and its reversal by galactose. [PDF]

Virulence
Li X, Wu JQ, Long XR, Hu SB, Jiang M.
europepmc   +1 more source

Glucocorticoid Treatment Dampens Kynurenine Pathway Activation and Cytokine Release in Immune Stimulated Human Microglia. [PDF]

Int J Tryptophan Res
Esposito Soccoio M, Mason RP, Devilliers J, Feuda R, Collier MEW, Giorgini F.   +5 more
europepmc   +1 more source