Results 21 to 30 of about 441,995 (314)

Volumetric MRI-Based Biomarkers in Huntington's Disease: An Evidentiary Review

open access: yesFrontiers in Neurology, 2021
Huntington's disease (HD) is an autosomal-dominant inherited neurodegenerative disorder that is caused by expansion of a CAG-repeat tract in the huntingtin gene and characterized by motor impairment, cognitive decline, and neuropsychiatric disturbances ...
Kirsi M. Kinnunen   +91 more
doaj   +1 more source

Path Constitution in Family Business Succession: Evidence from A Longitudinal Case Study

open access: yes, 2023
Family businesses balance profit with family, employee, and consumer needs and touch almost every facet of the private and public sectors. At the same time, family businesses must manage the challenging processes attributed to the critical, never-ending ...
Duckworth-Chambless, Toney L
core   +1 more source

Thinking Inside the Box: Simple Methods to Evaluate Complex Treatments

open access: yesJournal of Methods and Measurement in the Social Sciences, 2011
We risk ignoring cheaper and safer medical treatments because they cannot be patented, lack profit potential, require too much patient-contact time, or do not have scientific results. Novel medical treatments may be difficult to evaluate for a variety of
J. Michael Menke
doaj   +1 more source

Metadata Framework to Support Deployment of Digital Health Technologies in Clinical Trials in Parkinson’s Disease

open access: yesSensors, 2022
Sensor data from digital health technologies (DHTs) used in clinical trials provides a valuable source of information, because of the possibility to combine datasets from different studies, to combine it with other data types, and to reuse it multiple ...
Derek L. Hill   +16 more
doaj   +1 more source

Evaluating the Substantive Representation of Women and Domestic Violence Legislation in England and Wales: a Critical Path Approach [PDF]

open access: yes, 2018
More women entering politics has led to questions regarding so-called ‘women’s issues’ and whether female representatives make a difference in reference to these issues.
Kitchen, A.
core   +1 more source

Extracting Critical Path Graphs from MPI Applications [PDF]

open access: yes, 2005
The critical path is one of the fundamental runtime characteristics of a parallel program. It identifies the longest execution sequence without wait delays.
Schulz, M, Martin Schulz
core   +1 more source

Patient-Reported Outcome (PRO) Consortium translation process: consensus development of updated best practices

open access: yesJournal of Patient-Reported Outcomes, 2018
This paper describes the rationale and goals of the Patient-Reported Outcome (PRO) Consortium’s instrument translation process. The PRO Consortium has developed a number of novel PRO measures which are in the process of qualification by the U.S. Food and
Sonya Eremenco   +4 more
doaj   +1 more source

A bag-of-paths node criticality measure [PDF]

open access: yesNeurocomputing, 2018
This work compares several node (and network) criticality measures quantifying to which extend each node is critical with respect to the communication flow between nodes of the network, and introduces a new measure based on the Bag-of-Paths (BoP) framework.
Lebichot, Bertrand, Saerens, Marco
openaire   +3 more sources

Non-Small Cell Lung Cancer Symptom Assessment Questionnaire (NSCLC-SAQ): Measurement Properties and Estimated Clinically Meaningful Thresholds From a Phase 3 Study

open access: yesJTO Clinical and Research Reports, 2022
Introduction: The NSCLC Symptom Assessment Questionnaire (NSCLC-SAQ) was developed to assess NSCLC symptom severity in accordance with Food and Drug Administration evidentiary expectations leading to Food and Drug Administration qualification in 2018 ...
Paul Williams, MPH   +7 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

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