Results 91 to 100 of about 9,005,815 (383)

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

open access: yesFEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan   +10 more
wiley   +1 more source

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

open access: yesFEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez   +3 more
wiley   +1 more source

Assessing the reproducibility, stability, and biological interpretability of multimodal computed tomography image features for prognosis in advanced non‐small cell lung cancer

open access: yesiRADIOLOGY
Background Despite the existence of proposed prognostic features on computed tomography (CT) for patients with advanced‐stage non‐small cell lung cancer (NSCLC), including radiologists' handcrafted (RaH) features, radiomics features, and deep learning ...
Jiajun Wang   +7 more
doaj   +1 more source

Critical Pathways

open access: yesNursing Management (Springhouse), 1998
Hospital managers initiate a nurse orientation program modeled after critical pathways. The structure allows them to assess nurses' competency while providing experience.
Richard J. Francis, Catherine Batsie
openaire   +3 more sources

Mathematical Teaching Strategies: Pathways to Critical Thinking and Metacognition.

open access: yes, 2015
A teacher that emphasizes reasoning, logic and validity gives their students access to mathematics as an effective way of practicing critical thinking. All students have the ability to enhance and expand their critical thinking when learning mathematics.
Hui Su, F. Ricci, M. Mnatsakanian
semanticscholar   +1 more source

Dys-regulated Gene Expression Networks by Meta-Analysis of Microarray Data on Oral Squamous Cell Carcinoma [PDF]

open access: yes, 2010
Background: Oral squamous cell carcinoma (OSCC) is the sixth most common type of carcinoma worldwide. Development of OSCC is a multi-step process involving genes related to cell cycle, growth control, apoptosis, DNA damage response and other cellular ...
Chao Li   +5 more
core   +1 more source

Risks from low dose/dose rate radiation: what an understanding of DNA damage response mechanisms can tell us [PDF]

open access: yes, 2009
The DNA damage response (DDR) mechanisms represent a vital line of defense against exogenous and endogenous DNA damage to enhance two distinct outcomes, survival and the maintenance of genomic stability. The latter is critical for cancer avoidance.
Jeggo, Peggy A.
core   +2 more sources

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

White matter pathways critical for language are also critical for resolving proactive interference in working memory

open access: yesFrontiers in Psychology, 2014
Background White matter pathways connecting brain regions involved in language processing in the left prefrontal (PFC) and temporal cortices have been found to play a critical role in language comprehension (Turken and Dronkers, 2011). Among the frontal
Stephanie Kathleen Ries   +2 more
doaj   +1 more source

Signaling Cross Talk between TGF-β/Smad and Other Signaling Pathways.

open access: yesCold Spring Harbor Perspectives in Biology, 2017
Cytokines of the transforming growth factor β (TGF-β) family, including TGF-βs, bone morphogenic proteins (BMPs), activins, and Nodal, play crucial roles in embryonic development and adult tissue homeostasis by regulating cell proliferation, survival ...
K. Luo
semanticscholar   +1 more source

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