Results 111 to 120 of about 9,005,815 (383)
Glucose sensor O-GlcNAcylation coordinates with phosphorylation to regulate circadian clock. [PDF]
Posttranslational modifications play central roles in myriad biological pathways including circadian regulation. We employed a circadian proteomic approach to demonstrate that circadian timing of phosphorylation is a critical factor in regulating ...
Allen, Jasmina J+10 more
core +1 more source
A stepwise emergence of evolution in the RNA world
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Analysis of literary productions on the use of therapeutic play in clinical child [PDF]
This study aimed to survey and describe the scientific production on the use of therapeutic play as a resource facilitator in assisting the child during the performance ofclinical procedures by the healthteam.the strategy is through the integrative ...
Dione Viero Viana+2 more
doaj
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp+5 more
wiley +1 more source
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro+2 more
wiley +1 more source
Barriers to Electrification: Analyzing Critical Delays and Pathways Forward
This paper extensively explores the intricate nuances surrounding the delayed transition to new business models for electric vehicles. While there is commendable clarity regarding stakeholders, model possibilities, emission-reduction strategies, state ...
Beatriz Amante García+1 more
doaj +1 more source
Editorial: Different pathways into critical whiteness studies [PDF]
This special issue explores the complexities of critical whiteness studies methodologies. We decided upon critical whiteness studies (CWS) as our nodal point for this special issue since we believe whiteness often stays unchallenged as un-articulated and
Pedersen, Linda, Samaluk, Barbara
core
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt+4 more
wiley +1 more source
Protecting Critical Infrastructure by Identifying Pathways of Exposure to Risk [PDF]
Increasingly, our critical infrastructure is managed and controlled by computers and the information networks that connect them. Cyber-terrorists and other malicious actors understand the economic and social impact that a successful attack on these ...
Philip O’Neill
doaj
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel+2 more
wiley +1 more source