Differential Hydrogen Bonding in Human CYP17 Dictates Hydroxylation versus Lyase Chemistry [PDF]
, 2013 Consequences of alternative H-bonding: Raman spectra of oxygenated intermediates of Nanodisc-incorporated human CYP17 in the presence of natural substrates (pregnenolone and progesterone) directly confirm that substrate structure effectively alters ...
Gregory, Michael +3 more
core +2 more sources
Glutamate, Ornithine, Arginine, Proline, and Polyamine Metabolic Interactions: The Pathway Is Regulated at the Post-Transcriptional Level [PDF]
, 2016 The metabolism of glutamate into ornithine, arginine, proline, and polyamines is a major network of nitrogen-metabolizing pathways in plants, which also produces intermediates like nitric oxide, and γ-aminobutyric acid (GABA) that play critical roles in ...
Boubker eBarchi +7 more
core +11 more sources
Ranking the importance of nuclear reactions for activation and transmutation events
, 2015 Pathways-reduced analysis is one of the techniques used by the Fispact-II nuclear activation and transmutation software to study the sensitivity of the computed inventories to uncertainties in reaction cross-sections. Although deciding which pathways are
Arter, Wayne +3 more
core +1 more source
An evaluation of DNA-damage response and cell-cycle pathways for breast cancer classification [PDF]
, 2014 Accurate subtyping or classification of breast cancer is important for ensuring proper treatment of patients and also for understanding the molecular mechanisms driving this disease.
Fard, Atefeh Taherian +2 more
core +5 more sources
Pathways into multiple exclusion homelessness in seven UK cities [PDF]
, 2012 This paper interrogates pathways into multiple exclusion homelessness (MEH) in the UK and, informed by a critical realist theoretical framework, explores the potential causal processes underlying these pathways.
Bramley, Glen +2 more
core +1 more source
A clinical pathway for early diagnosis and initial management of Pott’s puffy tumor in children [PDF]
Pediatric Emergency Medicine JournalPurpose Pott’s puffy tumor (PPT), characterized by frontal bone osteomyelitis and subperiosteal abscess, typically arises as a complication of head trauma or frontal sinusitis and is associated with diverse triggers.
Cecilia Banda +5 more
doaj +1 more source
Deficiency of G1 regulators P53, P21Cip1 and/or pRb decreases hepatocyte sensitivity to TGFbeta cell cycle arrest [PDF]
, 2015 TGFbeta is critical to control hepatocyte proliferation by inducing G1-growth arrest through multiple pathways leading to inhibition of E2F transcription activity.
Bellamy, Christopher O +4 more
core +1 more source
The pivotal role of nursing personnel in burn care
Indian Journal of Plastic Surgery, 2010 The nurses play an important role in the overall management of a burn patient. They must be well versed with the various protocols available that can be used to rationally manage a given situation. The management not only involves medical care but also a
Elisabeth Greenfield
doaj +1 more source
Molecular Signaling Pathways and Therapeutic Targets in Hepatocellular Carcinoma
Cancers, 2020 Hepatocellular carcinoma (HCC) is a complex biological process and is often diagnosed at advanced stages with no effective treatment options. With advances in tumor biology and molecular genetic profiling, several different signaling pathways and ...
Manali Dimri, A. Satyanarayana
semanticscholar +1 more source
Dynamics of Nucleation in the Ising Model [PDF]
, 1994 Reactive pathways to nucleation in a three-dimensional Ising model at 60% of the critical temperature are studied using transition path sampling of single spin flip Monte Carlo dynamics.
Caruncho, H. J. +6 more
core +2 more sources