Results 71 to 80 of about 2,386,191 (312)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Surface reconstruction and ferroelectricity in PbTiO$_3$ thin films
, 2005 Surface and ferroelectric properties of PbTiO$_3$ thin films are investigated using an interatomic potential approach with parameters computed from first-principles calculations.
A. Munkholm +6 more
core +1 more source
Current quark mass effects on chiral phase transition of QCD in the improved ladder approximation [PDF]
, 2001 Current quark mass effects on the chiral phase transition of QCD is studied in the improved ladder approximation. An infrared behavior of the gluon propagator is modified in terms of an effective running coupling.
A. Barducci +71 more
core +3 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Zeros of the Partition Function and Pseudospinodals in Long-Range Ising Models
, 2003 The relation between the zeros of the partition function and spinodal critical points in Ising models with long-range interactions is investigated. We find the spinodal is associated with the zeros of the partition function in four-dimensional complex ...
A.M. Ferrenberg +18 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
General Procedure for Formulation of Multiaxial Fatigue Failure Criteria in Frequency Domain [PDF]
MATEC Web of Conferences, 2019 Fatigue life assessment under multiaxial loading conditions needs the use of multiaxial fatigue failure criteria. There are many formulations of such criteria which are usually divided in the groups of critical plane criteria and invariants based ...
Niesłony Adam +2 more
doaj +1 more source
Algebraic vortex liquid theory of a quantum antiferromagnet on the kagome lattice [PDF]
, 2007 There is growing evidence from both experiment and numerical studies that low half-odd integer quantum spins on a kagome lattice with predominant antiferromagnetic near neighbor interactions do not order magnetically or break lattice symmetries even at ...
J. Alicea +5 more
core +2 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source