Results 151 to 160 of about 7,145,149 (347)
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson+11 more
wiley +1 more source
We report the complex dielectric function ε = ε1 + iε2 of MoS2/WS2 and WS2/MoS2 heterostructures and their constituent monolayers MoS2 and WS2 for an energy range from 1.5 to 6.0 eV and temperatures from 39 to 300 K.
Hoang Tung Nguyen+7 more
doaj +1 more source
Thermodynamic Derivation of Scaling at the Liquid-Vapor Critical Point. [PDF]
Obeso-Jureidini JC+2 more
europepmc +1 more source
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu+11 more
wiley +1 more source
Analysis of Shell Egg Pasteurization Using Computational Fluid Dynamics
In the present work, the thermal pasteurization process of shell eggs was studied through Computational Fluid Dynamics. For large-size eggs (63–72 g), the required heating times at several different heating medium (water) temperatures, namely 54, 56, 58,
Pavlos-Antonios Sampanis+3 more
doaj +1 more source
From Critical Point to Critical Point: The Two-States Model Describes Liquid Water Self-Diffusion from 623 to 126 K. [PDF]
Corsaro C, Fazio E.
europepmc +1 more source
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez+17 more
wiley +1 more source
Optimized superconductivity in the vicinity of a nematic quantum critical point in the kagome superconductor Cs(V1-xTix)3Sb5. [PDF]
Sur Y, Kim KT, Kim S, Kim KH.
europepmc +1 more source
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source