Results 111 to 120 of about 3,262,666 (184)

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Variational Methods and Critical Point Theory

Abstract and Applied Analysis, 2012
M. Victoria Otero-Espinar, Juan J. Nieto, Donal O'Regan, Kanishka Perera   +3 more
doaj   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Variational Methods and Critical Point Theory 2013

Abstract and Applied Analysis, 2013
M. Victoria Otero-Espinar, Juan J. Nieto, Donal O’Regan, Kanishka Perera   +3 more
doaj   +1 more source

Infinite dimensional extensions of the Landesman-Lazer theorem

Electronic Journal of Differential Equations, 2021
Martin Schechter
doaj  

A perspective on the contributions of Alan C. Lazer to critical point theory

Electronic Journal of Differential Equations, 2000
Over the last thirty five years Professor Alan C. Lazer has been a leading figure in the development of min-max methods and critical point theory for applications to partial differential equations.
Alfonso Castro
doaj  

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Minimax principles for critical-point theory in applications to quasilinear boundary-value problems

Electronic Journal of Differential Equations, 2000
Using the variational method developed by the same author in [7], we establish the existence of solutions to the equation $-Delta_p u = f(x,u)$ with Dirichlet boundary conditions.
A. R. El Amrouss, M. Moussaoui
doaj  

Infinitely many positive solutions for p-Laplacian equations with singular and critical growth terms

Boundary Value Problems
In this paper, we study the existence of multiple solutions for the following nonlinear elliptic problem of p-Laplacian type involving a singularity and a critical Sobolev exponent { − Δ p u = u p ∗ − 1 + λ | u | γ − 1 u , in Ω , u = 0 , on ∂ Ω ...
Chen-Xi Wang, Hong-Min Suo
doaj   +1 more source