Results 111 to 120 of about 1,342,909 (347)

An Exposition on Critical Point Theory with Applications

open access: yesCurrent Research in Statistics & Mathematics
Critical Point Theory plays a pivotal role in the study of Partial Differential Equations (PDEs), particularly in investigating the existence, uniqueness, and multiplicity of weak solutions to elliptic PDEs under specified boundary conditions. This article offers a concise survey of key concepts, including differentiation on Banach spaces, the analysis
openaire   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

A perspective on the contributions of Alan C. Lazer to critical point theory

open access: yesElectronic Journal of Differential Equations, 2000
Over the last thirty five years Professor Alan C. Lazer has been a leading figure in the development of min-max methods and critical point theory for applications to partial differential equations.
Alfonso Castro
doaj  

The properties of the critical point in electroweak theory

open access: yes, 1999
We study the properties of the electroweak theory in the vicinity of the critical point --- the endpoint of the first order phase transition line that exists in a wide class of theories, including the Standard Model and a part of the parameter space of the Minimal Supersymmetric Standard Model.
openaire   +2 more sources

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

open access: yesMolecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef   +10 more
wiley   +1 more source

Infinite dimensional extensions of the Landesman-Lazer theorem

open access: yesElectronic Journal of Differential Equations, 2021
Martin Schechter
doaj  

Home - About - Disclaimer - Privacy