Results 101 to 110 of about 13,119,461 (251)
Politics of Representations in the Media and Intercultural Understanding. A Critical Theory Perspective. [PDF]
openThis thesis examines the politics of representations in the media and its implications for intercultural understanding, employing a critical theory perspective.
PECHENINA, ANASTASIIA
core
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
The Set-Point Theory of Well-Being Needs Replacing: On the Brink of a Scientific Revolution? [PDF]
Set-point theory has dominated the field of subjective well-being (SWB). It has served as a classic Kuhn research paradigm, being extended and refined for thirty years totake in new results. The central plank of the theory is that adult set-points do not
Bruce Headey
core
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Research Handbook on Critical Legal Theory
, 2019 Critical theory, characteristically linked with the politics of theoretical engagement, covers the manifold of the connections between theory and praxis.
core +1 more source
A perspective on the contributions of Alan C. Lazer to critical point theory
Electronic Journal of Differential Equations, 2000 Over the last thirty five years Professor Alan C. Lazer has been a leading figure in the development of min-max methods and critical point theory for applications to partial differential equations.
Alfonso Castro
doaj
Perturbations of critical values in nonsmooth critical point theory
, 1996 Several theorems about the perturbation of critical values for continuous functionals are proved. Their applications to eigenvalue problems for variational inequalities are given.
DEGIOVANNI M., LANCELOTTI, SERGIO
openaire +3 more sources
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source