Results 81 to 90 of about 3,726,336 (290)
Morse Thoery of Saddle Point Reduction with Applications
AxiomsIn this paper, we demonstrate that when saddle point reduction is applicable, there is a clear relationship between the Morse index and the critical groups before and after the reduction.
Ran Yang, Qin Xing
doaj +1 more source
, 1993 We study the random walk representation of the two-point function in statistical mechanics models near the critical point. Using standard scaling arguments we show that the critical exponent $\nu$ describing the vanishing of the physical mass at the ...
C. Itzykson +4 more
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Existence of homoclinic orbits for a class of nonlinear functional difference equations
Electronic Journal of Differential Equations, 2016 By using critical point theory, we prove the existence of a nontrivial homoclinic orbit for a class of nonlinear functional difference equations. Our conditions on the nonlinear term do not need to satisfy the well-known global Ambrosetti-Rabinowitz ...
Xia Liu, Tao Zhou, Haiping Shi
doaj
Bulletin of Mathematical SciencesDue to the essential difficulty of establishing an appropriate variational framework on a suitable working space, how to apply the critical point theory for showing the existence and multiplicity of periodic solutions of continuous-time difference ...
Genghong Lin +3 more
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Chain length dependence of the polymer-solvent critical point parameters
, 1996 We report grand canonical Monte Carlo simulations of the critical point properties of homopolymers within the Bond Fluctuation model. By employing Configurational Bias Monte Carlo methods, chain lengths of up to N=60 monomers could be studied.
Ginzburg V. I. +5 more
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Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Multiplicity of Homoclinic Solutions for Fractional Hamiltonian Systems with Subquadratic Potential
Entropy, 2017 In this paper, we study the existence of homoclinic solutions for the fractional Hamiltonian systems with left and right Liouville–Weyl derivatives. We establish some new results concerning the existence and multiplicity of homoclinic solutions for the ...
Neamat Nyamoradi +3 more
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source