Results 41 to 50 of about 419,462 (262)
Sign-changing solutions for some nonlinear problems with strong resonance
Boundary Value Problems, 2011 By means of critical point and index theories, we obtain the existence and multiplicity of sign-changing solutions for some elliptic problems with strong resonance at infinity, under weaker conditions.
Qian Aixia
doaj
Multiple Solutions for a Nonlinear Fractional Boundary Value Problem via Critical Point Theory
Journal of Function Spaces, 2017 This paper is concerned with the existence of multiple solutions for the following nonlinear fractional boundary value problem: DT-αaxD0+αux=fx,ux, x∈0,T, u0=uT=0, where α∈1/2,1, ax∈L∞0,T with a0=ess infx∈0,Tax>0, DT-α and D0+α stand for the left and ...
Yang Wang, Yansheng Liu, Yujun Cui
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Sing-changing solutions for nonlinear problems with strong resonance
Electronic Journal of Differential Equations, 2012 Using critical point theory and index theory, we prove the existence and multiplicity of sign-changing solutions for some elliptic problems with strong resonance at infinity, under weaker conditions than in the references.
Aixia Qian
doaj
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Periodic solutions for second order delay Duffing equation via critical point theory
Electronic Journal of Differential Equations, 2013 This article concerns the periodic problem of second order delay Duffing equation with cross resonance condition. Using critical point theory and homotopy methods, we obtain sufficient conditions for the existence of periodic solutions.
Jingrui Zhang, Yi Cheng, Changqin Yuan
doaj
Theory of the Many-Body Localization Transition in One-Dimensional Systems
Physical Review X, 2015 We formulate a theory of the many-body localization transition based on a novel real-space renormalization group (RG) approach. The results of this theory are corroborated and intuitively explained with a phenomenological effective description of the ...
Ronen Vosk, David A. Huse, Ehud Altman
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source