Results 71 to 80 of about 3,581,339 (338)

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Applications of Local Linking to Critical Point Theory

open access: yesJournal of Mathematical Analysis and Applications, 1995
Let \(f\in C^1 (X, \mathbb{R})\) satisfy a local linking condition at 0, i.e. the Banach space \(X\) splits as \(X= X^1 \oplus X^2\), \(f(u) \geq 0\) for \(u\in X^1\), \(|u|\leq r\), and \(f(u)\leq 0\) for \(u\in X^2\), \(|u|\leq r\); for some \(r>0\).
Michel Willem, Sj. Li
openaire   +3 more sources

Ferromagnetic Transition in One-Dimensional Itinerant Electron Systems

open access: yes, 2004
We use bosonization to derive the effective field theory that properly describes ferromagnetic transition in one-dimensional itinerant electron systems.
Kun Yang, M. E. Fisher
core   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Periodic solutions to a class of distributed delay differential equations via variational methods

open access: yesAdvances in Nonlinear Analysis, 2023
In this article, we study the existence of periodic solutions to a class of distributed delay differential equations. We transform the search for periodic solutions with the special symmetry of a delay differential equation to the problem of finding ...
Xiao Huafeng, Guo Zhiming
doaj   +1 more source

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

open access: yesFEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke   +2 more
wiley   +1 more source

Sign-changing solutions for some nonlinear problems with strong resonance

open access: yesBoundary Value Problems, 2011
By means of critical point and index theories, we obtain the existence and multiplicity of sign-changing solutions for some elliptic problems with strong resonance at infinity, under weaker conditions.
Qian Aixia
doaj  

Theory of the Many-Body Localization Transition in One-Dimensional Systems

open access: yesPhysical Review X, 2015
We formulate a theory of the many-body localization transition based on a novel real-space renormalization group (RG) approach. The results of this theory are corroborated and intuitively explained with a phenomenological effective description of the ...
Ronen Vosk, David A. Huse, Ehud Altman
doaj   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

open access: yesFEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Sing-changing solutions for nonlinear problems with strong resonance

open access: yesElectronic Journal of Differential Equations, 2012
Using critical point theory and index theory, we prove the existence and multiplicity of sign-changing solutions for some elliptic problems with strong resonance at infinity, under weaker conditions than in the references.
Aixia Qian
doaj  

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