Results 71 to 80 of about 390,400 (307)

Range of semilinear operators for systems at resonance

open access: yesElectronic Journal of Differential Equations, 2012
For a vector function $u:mathbb{R} o mathbb{R}^N $ we consider the system $$displaylines{ u''(t)+ abla G(u(t))= p(t)cr u(t)=u(t+T), }$$ where $G: mathbb{R}^N o mathbb{R}$ is a $C^1$ function.
Pablo Amster, Mariel Paula Kuna
doaj  

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Heteroclinic orbits of a second order nonlinear difference equation

open access: yesElectronic Journal of Differential Equations, 2017
This article concerns a second-order nonlinear difference equation. By using critical point theory, the existence of two heteroclinic orbits is obtained. The main method used is variational.
Haiping Shi, Xia Liu, Tao Zhou
doaj  

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

A modified zero energy critical point theory with applications to several nonlocal problems

open access: yesElectronic Journal of Qualitative Theory of Differential Equations
In this paper, we devote ourselves to considering a modified zero energy critical point theory for a specific set of functionals denoted as $\Phi_{\mu}$, defined within the confines of a uniformly convex Banach space.
Xinzhong Liang, Binlin Zhang
doaj   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Critical point theory for symmetries with fixed points

open access: yes, 2010
Gegenstand der Arbeit ist die Suche nach kritischen Punkten einer stetig differenzierbarer Funktion f auf einer Banach-Mannigfaltigkeit X, die invariant unter der Wirkung einer (kompakten Lie-) Symmetriegruppe G ist. Es gebe eine kompakte G-Mannigfaltigkeit M und eine G-äquivariante Surjektion von X auf M mit einem G-äquivarianten Schnitt, so dass sich
Born, Stefan   +1 more
openaire   +3 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

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