Results 141 to 150 of about 6,939,801 (335)

Dispatches from the frontlines: A critical care nurse's response to COVID19 [PDF]

, 2020
Joshua C. Allen
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

A successful partnership model for COVID‐19 vaccination in Aboriginal communities in New South Wales

Australian and New Zealand Journal of Public Health, 2022
Tamara Riley, Jill Guthrie, Lisa Whop, Nick Walsh, Angie Jackson, Tarun Weeramanthri   +5 more
doaj   +1 more source

Changes in cytokine concentrations during passage through a granulocyte and monocyte adsorption column in a porcine lipopolysaccharide-induced inflammation model

Renal Replacement Therapy
Background Sepsis 3 definitions have shifted the focus from nonspecific inflammation to sepsis as an organ dysfunction caused by a dysregulated host response to infection.
Tomoyuki Nakamura, Kazuhiro Moriyama, Toshikazu Sakai, Yu Kato, Osamu Nishida   +4 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

A Critical Review of In Vitro Methodologies for Studying Inflammatory Responses in Human Dental Pulp Cell Cultures [PDF]

Shelly Arora, Finn Gordon Gilroy, Lara T. Friedlander, Haizal Mohd Hussaini, Henry F. Duncan, Peter Cathro, Paul R. Cooper   +6 more
openalex   +1 more source

Tackling Covid-19: Critical Evaluation of India’s Response

, 2020
Shibu John
openalex   +2 more sources

Closed-Form Critical Earthquake Response of Elastic–Plastic Structures on Compliant Ground under Near-Fault Ground Motions [PDF]

, 2016
Kotaro Kojima, Izuru Takewaki
openalex   +1 more source

The CXCR3 chemokine receptor is critical for the protective immune response to Plasmodium parasite infection of the liver [PDF]

, 2023
Laura Reynolds, Rebecca Blyn, Lisa Wegmair, Patrick A. Lewis, Amina A. Sheikh, Vera Okolo, Brandon K. Wilder, Stefan H. I. Kappe, Nana Minkah   +8 more
openalex   +1 more source