Results 61 to 70 of about 6,950,475 (283)

Response Functions to Critical Shocks in Social Sciences: An Empirical and Numerical Study

, 2004
We show that, provided one focuses on properly selected episodes, one can apply to the social sciences the same observational strategy that has proved successful in natural sciences such as astrophysics or geodynamics. For instance, in order to probe the
B. M. ROEHNER, D. SORNETTE, De Podesta M., Dellago C., Durkheim E., Helmstetter A., J. V. ANDERSEN, Johansen A., Milgram S., Morse P.-M., Roehner B. M., Romer D., Scard J., Schumpeter J. A., Sornette D., Sornette D., Sornette D., Stauffer D., van Donselaar J., Varshney A.   +19 more
core   +1 more source

Critical Realism and Statistical Methods: A Response to Nash [PDF]

, 2007
This article offers a defence of critical realism in the face of objections Nash (2005) makes to it in a recent edition of this journal. It is argued that critical and scientific realisms are closely related and that both are opposed to statistical ...
Bhaskar R., Bhaskar R., Buckley W., Cruikshank J., David Scott, Giddens A., Manicas P., Organisation for Economic Cooperation and Development (OECD), Organisation for Economic Cooperation and Development (OECD), Outhwaite W., Porpora D., Rorty R., Scott D., Wilson R.   +13 more
core   +3 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Hospital preparedness for mass critical care during SARS-CoV-2 pandemic

Critical Care, 2020
Mass critical care caused by the severe acute respiratory syndrome corona virus 2 pandemic poses an extreme challenge to hospitals. The primary goal of hospital disaster preparedness and response is to maintain conventional or contingency care for as ...
Thomas Wurmb, Katja Scholtes, Felix Kolibay, Nora Schorscher, Georg Ertl, Ralf-Ingo Ernestus, Ulrich Vogel, Axel Franke, Barbara Kowalzik   +8 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Incidental Detection of Asymptomatic Upper Extremity Deep Vein Thrombosis in an Elderly Patient With Pulmonary Embolism

Acute Medicine & Surgery
Background Upper extremity deep vein thrombosis (UEDVT) is rare, accounting for 4%–10% of all DVT cases. Central venous catheterization and malignancy are primary risk factors, making cases without these factors uncommon.
Shuhei Uotani, Yoshihiro Aoki, Keita Iyama, Atsuko Tachikawa, Daisuke Sugawara, Kensuke Takahashi, Shuhei Yamano, Koichi Hayakawa, Osamu Tasaki   +8 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Non-linear, Finite Frequency Quantum Critical Transport from AdS/CFT

, 2011
Transport at a quantum critical point depends sensitively on the relative magnitudes of temperature, frequency and electric field. Here we used the gauge/gravity correspondence to compute the full temperature and, generally nonlinear, electric field ...
Karch, Andreas, Sondhi, S. L.
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Prognostic value of pulmonary dead space in patients with the acute respiratory distress syndrome. [PDF]

, 2011
A study published in the previous issue of Critical Care demonstrates that measurement of the pulmonary dead-space fraction is superior to hypoxemia as an indicator of a favorable physiologic response to prone positioning in patients with severe acute ...
Kallet, Richard H, Matthay, Michael A
core   +1 more source