Results 101 to 110 of about 559,608 (264)

DESIGN-STAGE ADJUSTMENT OF ROTOR CRITICAL SPEEDS

open access: yesAdvanced Engineering Research, 2011
Know-how and the computer-applied diversity algorithm (removal) for the operational and critical rotation speeds of the rotor at the design stage (critical frequencies adjustment) are offered.
Oleg O. Polushkin, Oleg A. Polushkin
doaj  

Use of Critical Speed Models from World Record Data to Estimate Limits of Human Ultra-Endurance Running Performance

open access: yesInternational Journal of Strength and Conditioning
Ultra-endurance running (>42.2km) has increased in popularity in recent years and elite finish times continue to improve. Models of Critical Speed (CS) - the highest speed which can be maintained without fatigue - are routinely developed from short ...
Garrett Manuel, Bollinger Lance
doaj   +1 more source

Critical Speed in a Curve - Update

open access: yesJournal of the National Academy of Forensic Engineers, 1990
V=(15 r f)l^(1/2)mph Where r is tire scuff radius of curvature in feet. f is the ratio of maximum lateral tire frictional force to vehicle weight. For the benefit of those readers unsure of the origin of the above equation, it is simply one possible solution to the undergraduate engineering dynamics text book problem involving a particle moving at ...
openaire   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

The Impact of Hollow Wear on the Stability of High-Speed Railway Vehicles

open access: yesApplied Sciences
Hollow wear on wheels is a common form of surface damage often observed in high-velocity vehicles. It is widely recognized that hollow wear of the wheel tread degrades the dynamic performance of rail vehicles, especially in the issue commonly referred to
Ling Zhang   +3 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Increased Exercise Tolerance in G6PD African Variant Mice Driven by Metabolic Adaptations and Erythrophagocytosis

open access: yesAntioxidants
Glucose-6-phosphate dehydrogenase (G6PD) deficiency, the most common enzymatic disorder, affects over 500 million people worldwide and is often linked to exercise intolerance due to oxidative stress, but its true impact on physical performance remains ...
Francesca I. Cendali   +15 more
doaj   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

open access: yesFEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima   +4 more
wiley   +1 more source

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