Results 61 to 70 of about 613,818 (299)

CRITICAL THEORY AND SOCIAL SCIENCE

open access: yesKanz Philosophia: A Journal for Islamic Philosophy and Mysticism
This research addresses the contemporary global conflict surrounding transformations in social life through the lens of Critical Theory. The urgency of analyzing the thoughts of Herbert Marcuse and Jürgen Habermas lies in their critical engagement with ...
Muhammad Faqih Nidzom   +2 more
doaj   +1 more source

CRÍTICA DEL PENSAMIENTO CRÍTICO. APUNTES PARA PENSAR LAS LUCHAS

open access: yesRevista Latinoamericana de Derechos Humanos, 2015
Resumen El texto pretende establecer un diálogo a lo interno de la tradición crítica, y, por tanto, desde las preocupaciones de fondo que han marcado su quehacer.
Manuel E. Gándara Carballido.
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

CRITICAL THEORY AND E-EDUCATION

open access: yesMetodički Vidici, 2014
There is an evident trend of an increased use of and positive attitudes towards e-Education and distance learning within the Croatian higher education system.
Josip T. Ćirić   +1 more
doaj  

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Critical theory and social inequality

open access: yesTempo Social
This paper argues that social inequality is possibly the core topic of any critical theory in the social sciences – for epistemological as well as ethical reasons.
Boike Rehbein
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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