Results 61 to 70 of about 247,682 (284)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Predicting Everyday Critical Thinking: A Review of Critical Thinking Assessments
Journal of IntelligenceOur ability to think critically and our disposition to do so can have major implications for our everyday lives. Research across the globe has shown the impact of critical thinking on decisions about our health, politics, relationships, finances ...
Heather A. Butler
doaj +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Critical Thinking Critical Thinking adds value
, 2012 Research at Cambridge Assessment has found that there is a significant advantage to Critical Thinking (CT) candidates in their other subjects. Further research also investigated how CT is delivered in schools and found that despite a number of challenges and obstacles, teachers were convinced of the value of CT.
openaire +1 more source
Reflections on the development and contribution of critical systems thinking and practice [PDF]
, 2010 Michael C. Jackson
openalex +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
A Research On The Critical Thinking Tendency of Nurse Managers
Sağlık ve Hemşirelik Yönetimi Dergisi, 2017 INTRODUCTION: The aim of this study is to determine the critical thinking trends of nurse managers working at Ministry of health training and research hospitals on the European side of İstanbul province and demographic characteristics of these trends ...
Muhteşem Baran, Fatma Balcı
doaj +1 more source
Thinking Creatively; Thinking Critically
Asian Social Science, 2009 The development of creative and critical thinking is seen as an encouragement to independent and student-centred learning. But what exactly do we mean when we talk about creative and critical thinking? When and why did these terms come into prominence in modern education?
openaire +2 more sources
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source