Results 111 to 120 of about 2,009 (183)

Inhibition of the Ubc9 E2 SUMO-conjugating enzyme–CRMP2 interaction decreases NaV1.7 currents and reverses experimental neuropathic pain

, 2018
We previously reported that destruction of the small ubiquitin-like modifier (SUMO) modification site in the axonal collapsin response mediator protein 2 (CRMP2) was sufficient to selectively decrease trafficking of the voltage-gated sodium channel NaV1 ...
Khanna, May, Tatiana Brustovetsky, May Khanna, Khanna, Rajesh, Aubin Moutal, Angie Dorame, Rajesh Khanna, Dustrude, Erik T., Brustovetsky, Nickolay, Perez-Miller, Samantha, Wang, Yue, Moutal, Aubin, Liberty François-Moutal, Brustovetsky, Tatiana, Erik T. Dustrude, Ju, Weina, Vijay Gokhale, Gokhale, Vijay, Samantha Perez-Miller, Yue Wang, Weina Ju, François-Moutal, Liberty, Dorame, Angie, Nickolay Brustovetsky   +23 more
core   +1 more source

High CRMP2 expression in peripheral T lymphocytes is associated with recruitment to the brain during virus-induced neuroinflammation.

, 2008
Collapsin Response Mediator Protein (CRMP)-2 is involved in T-cell polarization and migration. To address the role of CRMP2 in neuroinflammation, we analyzed its involvement in lymphocyte recruitment to the central nervous system in mouse infected with ...
Chounlamountri, I., M. Lafon, A. Bernard, Giraudon, P., I. Chounlamountri, Sagardoy, I., Vuaillat, C., Cavagna, S., Lafon, M., P. Giraudon, Bernard, A., Varrin-Doyer, M., C. Vuaillat, S. Cavagna, I. Sagardoy, M. Varrin-Doyer   +15 more
core   +1 more source

Enhancement of stress-induced memory formation in rats: The role of collapsin-response mediator protein 2 (CRMP2)

Интегративная физиология
The reported study investigates the impact of chronic stress on long-term memory formation and the expression of collapsin-response mediator protein 2 (CRMP2) within various brain structures in Wistar female rats.
Медина Илгар гызы Гасанова, Ариф Алиовсад оглы Мехтиев   +1 more
doaj   +1 more source

The Protein Interactome Of Collapsin Response Mediator Protein-2 (crmp2/dpysl2) Reveals Novel Partner Proteins In Brain Tissue.

, 2016
Collapsin response mediator protein-2 (CRMP2) is a CNS protein involved in neuronal development, axonal and neuronal growth, cell migration, and protein trafficking.
Hensley, Kenneth, Turck, Christoph W, Nascimento, Juliana M, Guest, Paul C, Cassoli, Juliana S, Martins-de-Souza, Daniel, Pinzon-Velasco, Andres M   +6 more
core   +1 more source

Alzheimer's disease-related changes in phosphorylation of collapsin response mediator protein 2 (CRMP2) and their effect on neuronal function

, 2015
CRMP2 was first identified in 1995 as a mediator of Sema3A signalization pathway which leads to axon growth cone collapse. Since then CRMP2 was designated as an essential cue during neuronal polarity estabilishment and neuronal growth in embryonic life ...
Škrlantová, Alice
core  

Role of the phosphatase PRL-3 and CRMP2 in the migration and invasion of uveal melanoma

, 2018
Le mélanome uvéal (MU) est une tumeur rare, affectant 500 à 600 nouveaux cas par an en France, mais il s’agit de la tumeur intraoculaire la plus fréquente chez l’adulte. Cette tumeur est due à la transformation des mélanocytes dérivés de la crête neurale
Duciel, Laura
core  

Rôle de la phosphatase PRL-3 et de CRMP2 dans la migration et l'invasion du mélanome uvéal [PDF]

, 2018
Uveal melanoma (UM) is a rare tumor (500 to 600 new cases by year in France) but this is the most common intraocular cancer in adult. This tumor is due to melanocytes transformation derived from neural crest and localized in uvea (choroid, ciliary body ...
Duciel, Laura
core  

Calycosin-7-O-β-D-Glucoside Facilitates Axonal Regrowth and Functional Recovery via Rho/ROCK Pathway Inhibition After Cerebral Ischemia/Reperfusion. [PDF]

Int J Mol Sci
Wang P, Yu A, Liang Y, Wang L.
europepmc   +1 more source

Suppression of Glial Activation in Tau Transgenic Mice Through Inhibition of CRMP2 Phosphorylation: a Morphometric Analysis. [PDF]

Neuromolecular Med
Li W, Kubota T, Guevara VA, Goshima Y, Saido TC, Ohshima T.   +5 more
europepmc   +1 more source

Lacosamide Is a Novel Drug That Improves AGTPBP1 Knockout-Mediated Impairment of Neuronal and Dopaminergic Function. [PDF]

Mol Neurobiol
Wang HP, Singh S, Wong LC, Hsu CJ, Li SC, Lee SJ, Lee CH, Lee WT.   +7 more
europepmc   +1 more source