Crocetin attenuates spared nerve injury-induced neuropathic pain in mice
, 2017 Crocetin is the main component of saffron and exhibits anti-oxidative and anti-inflammatory effects. Neuroinflammation and oxidative stress have been recognized to play a crucial role in the pathogenesis of neuropathic pain. We investigated the effect of
Yong Qiao +4 more
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Antibiofilm activity of carotenoid crocetin against Staphylococcal strains [PDF]
Staphylococcus aureus and Staphylococcus epidermidis stand as notorious threats to human beings owing to the myriad of infections they cause. The bacteria readily form biofilms that help in withstanding the effects of antibiotics and the immune system ...
Jintae Lee +2 more
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Advances in the study of crocetin sters, picrocrocin and flavonoids from saffron spice [PDF]
, 2009 Esta tesis pretende avanzar en el conocimiento de los ésteres de crocetina, picrocrocina y flavonoides de los extractos acuosos del azafrán especia. Para ello, se ha trabajado en distintos ámbitos: 1) su aislamiento, identificación y cuantificación; 2 ...
Sánchez Gómez, Ana María
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Monoolein liquid crystalline phases for topical delivery of crocetin
, 2018 The present investigation concerns the production and characterization of monoolein-water systems designed for cutaneous administration of crocetin. The different monoolein crystalline phases forming in the presence of crocetin as a function of added ...
Mariani, Paolo +15 more
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ROS-scavenging and Anti-tyrosinase Properties of Crocetin on B16F10 Murine Melanoma Cells
, 2018 Background: Crocus sativus (Iridaceae) has been traditionally used in the Iranian folk medicine and as a culinary additive. Major components of the plant that are responsible for biological properties are saffranal, crocin, picrocrocin and crocetin ...
Javad Baharara +7 more
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Iodine-induced synthetic method and pharmacokinetic study of cis- and trans-crocetin [PDF]
Objective:This experiment aimed to obtain the relatively rare cis-crocetin isomer from natural plants, which predominantly exist in the more stable all-trans configuration.
Xiaolin Li +9 more
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Chemistry, biochemistry, and mechanism of pharmacological actions of crocetin
Crocetin is an important naturally occurring substance that belongs to the carotenoids and is produced by few plant species. Among these plants, Crocus sativus (Saffron) is a rich source of crocetin and its conjugated compounds known as crocins.
Al-Babili, Salim, Zeb, Alam
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Antifibrotic effects of crocetin in scleroderma fibroblasts and in bleomycin-induced sclerotic mice
, 2013 OBJECTIVE: To investigate the antifibrotic effects of crocetin in scleroderma fibroblasts and in sclerotic mice. METHODS: Skin fibroblasts that were isolated from three systemic scleroderma (SSc) patients and three healthy subjects were treated with ...
Yinghua Song +5 more
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Anti-tumor effects of crocetin and related molecular targets
, 2018 Natural products have gained a wide popularity as chemopreventive and anti-cancer agents owing to their multi-mechanistic mode of action, availability and synergism with several conventional chemotherapeutic agents.
Sahebkar, A. +3 more
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Synergic effect of water-soluble components on the coloring strength of saffron spice
, 2010 The purpose of this paper was to study the synergic effect of water-soluble components of saffron, such as picrocrocin and kaempferol-3-O-glycoside, on its coloring strength (E1% 1 cm440 nm).
Maggi, Luana
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