Results 51 to 60 of about 3,677 (174)

Therapeutic Modulation of Inflammatory Signaling via Physalis Peruviana‐Derived Exosomes: A Targeted Effect on IKK/NFκB/STAT1

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 7, 15 April 2026.
Exosomes derived from Physalis peruviana contain various bioactive compounds, such as RNAs, proteins, and secondary metabolites. These exosomes have been shown to contain different types of carotenoids that may have therapeutic properties. Physalis peruviana exosomes are capable of exhibiting anti‐inflammatory effects by influencing the IKK/NFκB/STAT1 ...
Cristian Martínez Fajardo   +5 more
wiley   +1 more source

Bioengineered Isoflavone–Probiotic Functional Foods for Sustainable Modulation of Metabolic and Reproductive Health in PCOS

open access: yesFood Bioengineering, Volume 5, Issue 1, Page 45-72, March 2026.
Synergistic isoflavone‐probiotic action modulated metabolic, microbial and ovarian pathway ABSTRACT Polycystic ovary syndrome (PCOS) is a prevalent metabolic–endocrine disorder characterized by insulin resistance, hyperandrogenism, chronic inflammation, oxidative stress, and ovarian dysfunction, with growing evidence implicating gut microbiota ...
Jeyavelkumaran Renukadevi   +4 more
wiley   +1 more source

The Effect of Subchronic Administration of the Aqueous and Hydro-alcoholic Extracts of Crocus sativus from Estahbanat, Fars Province, on Mice

open access: yesArmaghane Danesh Bimonthly Journal, 2012
Background & aim: In Iranian traditional medicine, Crocus sativus L. has been defined as an exultant plant. The present study was undertaken to determine the effect of subchronic administration of aqueous and hydro-alcoholic extracts of Crocus sativus on
M Emamghoreishi, F Ghasemi
doaj  

Exploring the viral landscape of saffron through metatranscriptomic analysis

open access: yesVirus Research
Saffron (Crocus sativus L.), a historically significant crop valued for its nutraceutical properties, has been poorly explored from a phytosanitary perspective. This study conducted a thorough examination of viruses affecting saffron samples from Spanish
Cristian Martínez-Fajardo   +9 more
doaj   +1 more source

Obesity and Natural Products: Mechanisms, Therapeutic Potential, and Future Directions

open access: yesFood Science &Nutrition, Volume 14, Issue 3, March 2026.
Natural products such as EGCG, berberine, curcumin, and capsaicin modulate key metabolic pathways including AMPK activation, adipogenesis inhibition, and inflammatory signaling. While clinical trials demonstrate modest benefits on body weight and metabolic parameters, translational challenges related to bioavailability, dose feasibility, and regulatory
Ohoud M. Marie   +1 more
wiley   +1 more source

Nutrients and Heavy Metals in Flowers and Corms of the Saffron Crocus (Crocus sativus L.) [PDF]

open access: yesMedicinal & Aromatic Plants, 2016
We used ICP mass spectrometry and gas chromatography to examine the nutritional properties of the flower organs of saffron crocus grown in two cultivation fields. The pollenkitt consisted of a variety of mainly unsaturated fatty acids of dietary value, and fats of the same type were also on the anther wall.
Chichiricco G, Barbara Lanza
openaire   +2 more sources

Dietary Bioactives and Physical Activity in the Regulation of Hippocampal Neurogenesis and Cognitive Decline

open access: yesFood Science &Nutrition, Volume 14, Issue 3, March 2026.
Exercise and dietary polyphenols enhance hippocampal plasticity and cognitive function via complementary molecular mechanisms. Central pathways include BDNF signaling, inflammation control, and mitochondrial regulation. Although synergy is mainly supported by preclinical data, lifestyle‐based strategies show promise for brain health maintenance ...
Zhenyi Zhao, Sima‐sadat Sabihi
wiley   +1 more source

FT-Raman Spectra of Saffron (Crocus Stivus L.); A Possible Method for Standardization of Saffron [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2000
FT-Raman Spectra of Saffron (crocus sativus L.) with a partial assignment is reported. Based on the Raman data, it is concluded that main pigments in saffron are crocins and crocetin.
Amanollah Aminzadeh
doaj  

Neuronutraceuticals for Alzheimer's Disease Treatment: A Systematic Review of Randomised Controlled Trials Over the Last 20 Years

open access: yesPhytochemicals in Food and Medicine, Volume 1, Issue 1, March 2026.
This PROSPERO‐registered review analysed 37 RCTs on neuronutraceuticals for Alzheimer's disease. Despite diverse targets—amyloid/tau, inflammation, oxidative stress, metabolism, synaptic plasticity, cholinergic and hormonal—the evidence was of low quality. RoB2 flagged attrition (86.5%) and reporting bias (81%). Current data do not support clinical use;
Mehmet Akif Topcuoglu, Esen Saka
wiley   +1 more source

Florigen Activation Complex Dynamics and SVP‐Mediated Repression Orchestrate Temperature‐Regulated Flowering in Saffron

open access: yesPlant Biotechnology Journal, Volume 24, Issue 3, Page 1133-1151, March 2026.
ABSTRACT Saffron, a high‐value spice cultivated worldwide for its therapeutic and culinary uses, is a sterile triploid species, rendering conventional breeding approaches ineffective. This limitation underscores the need for molecular and biotechnological strategies for its genetic improvement. Flowering, a key determinant of saffron yield, is strongly
Diksha Kalia   +3 more
wiley   +1 more source

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