Food Frontiers, EarlyView.Engineered probiotics secretes fusion proteins which potentially neutralized the toxins secreted by other microbial communities. ABSTRACT On a global scale, the escalating burden of infectious diseases, predominantly attributed to bacterial pathogens, especially drug‐resistant strains, has progressed into a critical concern for clinical management and ...
Indu Singh +11 more
wiley +1 more source
Identifying patients with a high risk of relapse in quiescent Crohn's disease. The GETAID Group. The Groupe d'Etudes Thérapeutiques des Affections Inflammatoires Digestives. [PDF]
, 1995 Tarek Sahmoud +9 more
openalex +1 more source
Food Frontiers, EarlyView.CMTR‐Gel targeting to the inflamed mucosa by electrostatic interactions. ABSTRACT Natural drug‐food homology compounds have vast therapeutic potential, particularly for inflammatory bowel disease (IBD), but their poor water solubility, instability, and limited mucosal availability hinder their clinical translation.
Wenqiu Xu +7 more
wiley +1 more source
Edwardsiella tarda Infection Triggering Acute Relapse in Pediatric Crohn’s Disease
Case Reports in Infectious Diseases, 2019 Crohn’s disease exacerbations can often be associated with bacterial infections causing gastroenteritis. We report a child who experienced exacerbation of his Crohn’s disease associated with a positive stool culture for Edwardsiella tarda (E.
A. K. Li +3 more
doaj +1 more source
Analysis of Global Inequalities in Inflammatory Bowel Disease
Gut Medicine, EarlyView.ABSTRACT Background This study aims to rigorously assess socioeconomic and geographic inequalities in IBD burden globally. Methods Using data from the Global Burden of Disease (GBD) 2021 study, this research applies seven advanced summary measures of health inequality to assess regional disparities in inflammatory bowel disease (IBD) across four key ...
Baoyan Chen +12 more
wiley +1 more source
Epigenetic silencing of SOCS3 expression contributes to fibrosis in Crohn’s disease [PDF]
, 2017 Identified risk polymorphisms affecting the Jak-STAT3 pathway in patients with Crohn’s disease could affect TGF-β1 and collagen I expression and in the pathway’s negative regulator, SOCS3.
Kuemmerle, John F +2 more
core +1 more source
Editorial: visceral fat as a predictor of post‐operative recurrence of Crohn's disease [PDF]
, 2017 Ryan W. Stidham, Akbar K. Waljee
openalex +1 more source
Chinese Patent Medicine Ameliorate Ulcerative Colitis in Mice by Restoring the Th17/Treg Balance
Gut Medicine, EarlyView.ABSTRACT Background and Objective In China, Weichang'an Pill (WCAP) is a drug marketed for mild and moderate active ulcerative colitis (UC) but its mechanism is unknown. In the present study, the anti‐inflammatory mechanism of WCAP was investigated. Methods Dextran sulfate sodium (DSS) was used to induce UC in mice, which were divided into 4 groups (n =
Tao Zhang +6 more
wiley +1 more source
A29 HIGH DIMENSIONAL SINGLE CELL ANALYSIS OF IL-4 TREATED MACROPHAGES REVEALS A HETEROGENIC PHENOTYPE AND THE ABSENCE OF CD206+ SUBSETS IN CROHN'S DISEASE PATIENTS [PDF]
, 2023 B E Callejas +7 more
openalex +1 more source