Microscopic features of small bowel mucosa of patients with Crohn’s disease
Background Double-balloon enteroscopy enables performing numerous small bowel biopsies for pathologic analysis. However, most histopathological characteristics of Crohn’s disease are non-specific characteristics.
Yun Cui +7 more
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Oral manifestations of Crohn's disease [PDF]
Crohn's disease is a chronic granulomatous inflammatory bowel disease of unknown cause. Segments of the whole gastrointestinal tract may be involved, including the oral cavity.
Marković Ljiljana, Ljušković Bešir
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Multicentric Cutaneous Crohn's Disease: A Case Report and Review of Literature
A patient presented with skin lesions at sites not contiguous with Crohn's disease of the bowel and with specific histological features of Crohn's disease occurring two weeks from the onset of bowel symptoms.
Robert Prokopetz +3 more
doaj +1 more source
Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease [PDF]
Traditionally, Crohn's disease has been associated with a Th1 cytokine profile, while Th2 cytokines are modulators of ulcerative colitis. This concept has been challenged by the description of tolerising regulatory T cells (Treg) and by proinflammatory ...
Brand, Stephan
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Molecular prediction of disease risk and severity in a large Dutch Crohn's disease cohort [PDF]
Item does not contain fulltextBACKGROUND: Crohn's disease and ulcerative colitis have a complex genetic background. We assessed the risk for both the development and severity of the disease by combining information from genetic variants associated with ...
Bodegraven, A.A. van +15 more
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A rhodanine agent active against non-replicating intracellular Mycobacterium avium subspecies paratuberculosis. [PDF]
BACKGROUND: Antibiotic therapy targeting chronic mycobacterial disease is often ineffective due to problems with the emergence of drug resistance and non-replicating persistent intracellular antibiotic resistant phenotypes.
Bull, TJ +3 more
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Metastatic Crohn’s disease despite infliximab therapy [PDF]
Metastatic Crohn’s disease is a rare extraintestinal manifestation of Crohn’s disease. It is characterized by polymorphic skin lesions formed by non-caseating granulomas located on anatomical sites distant from the gastrointestinal tract.
Sara Campos +3 more
doaj +1 more source
Alterations of the CARD15/NOD2 gene and the impact on management and treatment of Crohn's disease patients [PDF]
The recent identification of the CARD15/NOD2 gene as a susceptibility locus for Crohn's disease represents an important step towards the delineation of the immuno-pathogenesis of inflammatory bowel disease.
Folwaczny, Christian +3 more
core +1 more source
Progress and Clinical Applications of Crohn’s Disease Exclusion Diet in Crohn’s Disease
Crohn’s disease is a chronic intestinal inflammatory disorder of unknown etiology. Although the pharmacotherapies for Crohn’s disease are constantly updating, nutritional support and adjuvant therapies have recently gained more attention.
Duo Xu +5 more
doaj +1 more source
Reactive angioendotheliomatosis (RAE) is a rare cutaneous vascular disorder, usually associated with systemic diseases. RAE has previously been described only in the skin, with the single exception of one case involving the intestine in a patient with ...
Hwajeong Lee, MD +1 more
doaj +1 more source

