Results 61 to 70 of about 144,849 (341)

Prediction of Perianal Fistula in Crohn’s Disease by Computed Tomography Enterography

open access: yesThe Turkish Journal of Gastroenterology
Background/Aims: The purpose of this study was to investigate whether computed tomography enterography can be used to predict the presence of perianal fistula in Crohn’s disease patients.
Genghuan Ni   +4 more
doaj   +1 more source

Arabinoxylans, inulin and Lactobacillus reuteri 1063 repress the adherent-invasive Escherichia coli from mucus in a musosa-comprising gut model [PDF]

open access: yes, 2016
The microbiota that colonises the intestinal mucus may particularly affect human health given its proximity to the epithelium. For instance, the presence of the adherent-invasive Escherichia coli (AIEC) in this mucosal microbiota has been correlated with
De Weirdt, Rosemarie   +6 more
core   +2 more sources

Polydopamine Nanodots Ameliorate Inflammatory Bowel Disease by Restoring Redox Homeostasis and Intestinal Microenvironment

open access: yesAdvanced Science, EarlyView.
A novel melanin‐based therapeutic composed of ultrasmall polydopamine nanodots is employed as an efficient oral formulation for the targeted treatment of inflammatory bowel disease. The potential therapeutic mechanism of polydopamine nanodots mainly involves the elimination of excessive oxidative stress, the reduction of ROS‐mediated proinflammatory ...
Zhen Ding   +11 more
wiley   +1 more source

Meckel's Diverticulum in Crohn's Disease

open access: yesCanadian Journal of Gastroenterology, 2001
Meckel's diverticulum is a congenital abnormality of the distal ileum associated with failed vitelline duct closure. Detailed pathological studies have estimated its frequency to be about 2% of the general population, and it has been anecdotally recorded
Hugh J Freeman
doaj   +1 more source

HLA-B27 Positivity: associated health implications [PDF]

open access: yes, 2011
HLA-B27 positivity makes the onset of autoimmune diseases such as uveitis, ankylosing spondylitis and Crohn's disease more likely to occur. Ankylosing spondylitis and Crohn's disease are two types of HLA-B27 positive diseases that demonstrate a direct ...
Cox, C. L.   +4 more
core   +1 more source

Telocytes in Crohn's disease [PDF]

open access: yesJournal of Cellular and Molecular Medicine, 2013
AbstractCrohn's disease (CD) is a relapsing chronic inflammatory disorder that may involve all the gastrointestinal tract with a prevalence of terminal ileum. Intestinal lesions have a characteristic discontinuous and segmental distribution and may affect all layers of the gut wall.
A. F. Milia   +7 more
openaire   +3 more sources

Intrinsic MicroRNA‐10a Restricts Regulatory T Cell Suppressive Function and Intestinal Repair by Coordinating Transcriptional, Metabolic, and Epithelial Repair Pathways

open access: yesAdvanced Science, EarlyView.
This study identifies microRNA‐10a (miR‐10a) as a key brake on regulatory T cell (Treg) suppressive function and intestinal repair. By targeting Blimp‐1, Uqcrq, and amphiregulin, miR‐10a restrains transcriptional, metabolic, and epithelial programs essential for Treg activity.
Wenjing Yang   +9 more
wiley   +1 more source

Esophageal Crohn's Disease Treated “Topically” with Swallowed Aerosolized Budesonide

open access: yesCase Reports in Medicine, 2010
Proximal Crohn's disease, involving the esophagus, the stomach, the duodenum, and the proximal jejunum, is uncommon. Treatment for proximal Crohn's disease is based on data derived from case series than from controlled trials.
Petros Zezos   +4 more
doaj   +1 more source

What constitutes failure of medical therapy in the changing landscape of Crohn's disease?

open access: yesLaparoscopic, Endoscopic and Robotic Surgery, 2022
The management of Crohn's disease has evolved rapidly in the era of immunomodulators and biologicals. Despite this, a significant proportion of patients with Crohn's disease ultimately require surgical management.
Nguyen Huynh   +3 more
doaj   +1 more source

Smoking in inflammatory bowel diseases: Good, bad or ugly? [PDF]

open access: yes, 2007
Smoking is an important environmental factor in inflammatory bowel disease (IBD), having different effects in ulcerative colitis (UC) and Crohn’s disease (CD).
Lakatos, László   +2 more
core   +1 more source

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