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Whereas typical Crohn’s disease is confined to the terminal ileum and presents with abdominal pain and diarrhea, gastroduodenal manifestations of Crohn’s disease are rare, with often asymptomatic patient presentations and inconclusive diagnostic testing.
Clive Jude Miranda+4 more
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Metastatic Crohn’s disease despite infliximab therapy [PDF]
Metastatic Crohn’s disease is a rare extraintestinal manifestation of Crohn’s disease. It is characterized by polymorphic skin lesions formed by non-caseating granulomas located on anatomical sites distant from the gastrointestinal tract.
Sara Campos+3 more
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Developing a non-invasive diagnostic model for pediatric Crohn’s disease using RNA-seq analysis
Introduction: Pediatric Crohn’s disease is a chronic inflammatory condition that affects the digestive system in children and adolescents. It is characterized by symptoms such as abdominal pain, diarrhea, weight loss, and malnutrition, and can also cause
Bin He+5 more
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44-year-old female known case of Crohn’s disease and depression who presented with a few hours’ history of severe abdominal pain and multiple episodes of vomiting faeculant matter.
Abela, Franklin, Dimech, Anthony Pio
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Progressive Primary Appendiceal Crohn’s Disease in a 21-Year-old Female
Crohn’s disease is an inflammatory bowel disorder that can affect any portion of the gastrointestinal tract, most commonly the terminal ileum near the ileocecal valve.
Cullen Roberts+3 more
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Context and Objectives Focally enhanced gastritis and macrophage microaggregates are found in the upper gastrointestinal involvement of Crohn’s disease, and may reflect an underlying defective innate immunity.
Marcia Henriques de MAGALHÃES-COSTA+5 more
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Smoking in inflammatory bowel diseases: Good, bad or ugly? [PDF]
Smoking is an important environmental factor in inflammatory bowel disease (IBD), having different effects in ulcerative colitis (UC) and Crohn’s disease (CD).
Lakatos, László+2 more
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Diet and gut microbiota are both important factors in the pathogenesis of Crohn’s disease, and changes in diet can lead to alteration in gut microbiome. However, there is still insufficient exploration on interaction within the gut microbiota under high ...
Yiming Zhao+8 more
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Detecting and managing small bowel Crohn’s disease – capsule endoscopy becoming a first line diagnostic method? [PDF]
Small bowel endoscopy is crucial for diagnosing small bowel Crohn’s disease, and capsule endoscopy is complemented by balloon-assisted enteroscopy to take biopsies and by magnetic resonance imaging to visualize enteral and extra-intestinal involvement ...
Albert, Jörg Gerhard+1 more
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Background Mutations or polymorphisms of genes that are associated with inflammasome functions are known to predispose individuals to Crohn’s disease and likely affect clinical presentations and responses to therapeutic agents in patients with Crohn’s ...
Harumi Jyonouchi, Lee Geng
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