Results 91 to 100 of about 102,860 (309)

Assigning function to genome wide association study variants associated with complex gastrointestinal disease [PDF]

, 2009
PhDThe genome‐wide association study era has identified numerous loci associated with many common polygenic diseases. The next challenge is to identify the functional consequences of these variants and elicit how they impact on disease risk.
Heap, Graham Alastair Richard
core  

6-thioguanine treatment in inflammatory bowel disease: A critical appraisal by a European 6-TG working party [PDF]

, 2006
Recently, the suggestion to use 6-thioguanine (6-TG) as an alternative thiopurine in patients with inflammatory bowel disease (IBD) has been discarded due to reports about possible (hepato) toxicity. During meetings arranged in Vienna and Prague in 2004,
Seiderer, J., Merwe, S. W. van der, Ochsenkühn, Thomas, Almer, S., Petritsch, W, Mulder, C. J. J, Seiderer, J, Vogelsang, H., Mulder, CJJ, Teml, A, Van Bodegraven, A. A., Teml, A., Herrlinger, K. R., Schwab, M., de Boer, NKH, Knoflach, P, van der Merwe, SW, Schwab, M, Reinisch, W., Ochsenkuhn, T, Reinisch, W, Knoflach, P., Petritsch, W., De Boer, N. K.H., De Boer, N. K. H, Van Der Merwe, S. W., Almer, Sven,, Vogelsang, H, Lukas, M., Ochsenkühn, T., van Bodegraven, AA, Lukas, M, Herrlinger, KR, Mulder, C. J.J., Bodegraven, A. A. van   +34 more
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Oral Prebiotic Polysaccharide Hydrogels Sustaining Colon Antibody Release Alleviate Inflammatory Bowel Disease

Advanced Science, EarlyView.
An orally administered prebiotic polysaccharide hydrogel (predaGel) based on inulin and alginate‐dopamine is stable in the stomach, adheres to the intestine, and degrades slowly in the colon. It enables site‐specific delivery of anti‐TNF‐α and anti‐IL‐12/23 antibodies, scavenges reactive oxygen species, and remodels gut microbiota, offering effective ...
Xinyi Dong, Huan He, Li Cao, Fenghua Meng, Zhiyuan Zhong   +4 more
wiley   +1 more source

Ustekinumab-induced Henoch-Schönlein purpura in Crohn’s disease: a case report and literature review [PDF]

Intestinal Research
Crohn’s disease is a chronic inflammatory disease of the digestive tract with extraintestinal manifestations, which include skin conditions, arthritis, ocular inflammation, and several autoimmune conditions. Dermatologic manifestations in Crohn’s disease
Merih Deniz Toruner, Tugce Guvenir, Volkan Yilmaz, Ramazan Erdem Er, Murat Toruner   +4 more
doaj   +1 more source

Nonspecific ileitis: Impact of histopathology and gastrointestinal ultrasound in achieving the diagnosis of Crohn's disease

JGH Open, 2022
Background and Aim Nonspecific ileitis is inflammation of the ileum without specific diagnostic features. A minority may go on to develop Crohn's disease, but optimal pathways of further investigation have not been established.
Rebecca L Smith, Kirstin M Taylor, Antony B Friedman, Ammar Majeed, Natalie Perera, Peter R Gibson   +5 more
doaj   +1 more source

MOESM1 of Vitamin D deficiency associated with Crohnâ s disease and ulcerative colitis: a meta-analysis of 55 observational studies

, 2019
Additional file 1: Method S1. Search strategy.
Li, Xi-Xi, Liu, Yang, Luo, Jie, Huang, Zhen-Dong, Zhang, Chao, Fu, Yan   +5 more
openaire   +1 more source

Toll-like receptor 4 and NOD2/CARD15 mutations in Hungarian patients with Crohn's disease: Phenotype-genotype correlations [PDF]

, 2005
AIM: To determine common NOD2/CARD15 mutations and TLR4 D299G polymorphism in Hungarian patients with CD. METHODS: A total of 527 unrelated patients with CD (male/female: 265/262, age: 37.1 (SD 7.6) years) and 200 healthy subjects were included.
Gasztonyi, Beáta, Mózsik, Gyula, Oesterreicher, Christoph, Szalay, Ferenc, Willheim-Polli, Claudia, Reinisch, Walter, Papp, János, Lakatos, Péter László, Molnár, Tamás, Altorjay, István, Tulassay, Zsolt, Ferenci, Péter, Lakatos, László   +12 more
core  

Long‐Term Outcomes After Stoma Creation in Crohn's Disease: A Retrospective Cohort Study of 422 Patients

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim Stoma creation is often required in Crohn's disease (CD), most commonly because of progressive anorectal disease. As stoma closure strongly influences long‐term quality of life and surgical decision‐making, this study evaluated the indications and long‐term outcomes of stoma creation in patients with CD.
Kentaro Nagano, Ryuichi Kuwahara, Yusuke Tomoo, Kurando Kusunoki, Yuki Horio, Kei Kimura, Kozo Kataoka, Masataka Ikeda, Motoi Uchino, Hiroki Ikeuchi   +9 more
wiley   +1 more source

Additional file 3: of Dietary treatment of Crohnâ s disease: perceptions of families with children treated by exclusive enteral nutrition, a questionnaire survey

, 2017
Survey on Dietary Treatment for Crohnâ s Disease Adult/Carer Version. (PDF 241 kb)
Svolos, Vaios, Gerasimidis, Konstantinos, Buchanan, Elaine, Curtis, Lee, Garrick, Vikki, Hay, Jacqueline, Laird, Susan, Munro, Joanna, Gaya, Daniel, Russell, Richard, Hansen, Richard   +10 more
openaire   +1 more source

Gender-stratified analysis of DLG5 R30Q in 4707 patients with Crohn disease and 4973 controls from 12 Caucasian cohorts [PDF]

, 2007
Background: DLG5 p. R30Q has been reported to be associated with Crohn disease ( CD), but this association has not been replicated in most studies. A recent analysis of gender-stratified data from two case-control studies and two population cohorts found
Vermeire, S, Cucchiara, S, Fisher, S A, Fisher, S. A., Cucchiara, S., Knafelz, D., Mathew, C., Parkes, M., Rutgeerts, P, Petermann, I, Müller-Myhsok, B., Török, H.-P., Ferraris, A, NEWMAN WG, Witt, H., Ferraris, A., Noble, C L, Valvano, M.R., Siminovitch, K. A., LAKATOS L, Ferguson, L R, Henckaerts, L., Barclay, M L, Witt, H, Mathew, C; id_orcid, CASTRO M, Shelling, A.N., BUNING C, DALLAPICCOLA B, FISHER SA, SHELLING AN, PETERMANN I, Dallapiccola, B, Barclay, M. L., NIMMO ER, Lakatos, L, Lakatos, Péter László, GLAS J, Tremelling, M, Noble, CL, Browning, BL, Noble, C.L., Valvano, M R, Liu, X, Lakatos, P L, Drummond, H., Rutgeerts, P., PARKES M, Noble, C. L., Siminovitch, KA, Mathew, C, Glas, J, Muller-Myhsok, B, CUCCHIARA, Salvatore, Ferguson, L.R., Browning, B. L., Nimmo, ER, Müller-Myhsok, Bertram, Barclay, ML, LAKATOS PL, Vermeire, S., TREMELLING M, Latiano, A., WITT H., Annese, V, Newman, W.G., Nimmo, E.R., Satsangi, J., Browning, B L, DRUMMOND H, BARCLAY ML, Lakatos, PL, MULLER MYHSOK B, Shelling, Andrew, Ferguson, L. R., PALMIERI O, Palmieri, O., Castro, M., Tremelling, M., Latiano, A, Glas, J., Nimmo, E. R., A. FERRARIS, Gearry, R.B., Newman, W. G., FERGUSON LR, Nimmo, E R, VERMEIRE S, Torok, H. P., Büning, C., SIMINOVITCH KA, Gearry, R B, Siminovitch, K A, Newman, WG, Gearry, RB, Annese, V., Huebner, C., HUEBNER C, Petermann, I., Dallapiccola, B., Bingham, S.A., Lakatos, P. L., LATIANO A, Torok, H, TOROK HP, Buning, C, KNAFELZ D, Gearry, R. B., Parkes, M, Newman, W. G.; id_orcid, Valvano, MR, BROWNING BL, Valvano, M. R., Drummond, H, Huebner, C, Lakatos, László, Barclay, M.L., GEARRY RB, MATHEW C, BINGHAM SA, Liu, X., SATSANGI J, Brand, S, Bingham, S, Glas, Jürgen, Siminovitch, K.A., Bingham, S. A., Browning, B.L., Knafelz, D, HENCKAERTS L, BRAND S, Palmieri, O, Shelling, A. N., Torok, H P, LIU X, Fisher, S.A., Brand, S., Ferguson, Lynnette, Lakatos, L., RUTGEERTS P, Satsangi, J, Shelling, A N, Fisher, SA, Brand, Stefan, Castro, M, Lakatos, P.L., VALVANO MR, Bingham, S A, ANNESE V, Newman, W G, Henckaerts, L, NOBLE CL   +151 more
core   +1 more source