Results 71 to 80 of about 102,860 (309)

Prediction of Perianal Fistula in Crohn’s Disease by Computed Tomography Enterography

The Turkish Journal of Gastroenterology
Background/Aims: The purpose of this study was to investigate whether computed tomography enterography can be used to predict the presence of perianal fistula in Crohn’s disease patients.
Genghuan Ni, Hongwei Zhao, Haiyan Shen, Senjuan Li, Weiqun Ao   +4 more
doaj   +1 more source

Adalimumab Dose-Escalation Therapy Is Effective in Refractory Crohn’s Disease Patients with Loss of Response to Adalimumab, Especially in Cases without Previous Infliximab Treatment

Case Reports in Gastroenterology, 2019
Background/Aims: Adalimumab dose escalation is one of the most important options in refractory Crohn’s disease patients with loss of response to adalimumab. The goal of this study was to evaluate the effectiveness of adalimumab dose escalation in Crohn’s
Taketo Suzuki, Tsutomu Mizoshita, Tomoya Sugiyama, Yoshikazu Hirata, Yoshihide Kimura, Yuka Suzuki, Tomonori Yamada, Hironobu Tsukamoto, Takashi Mizushima, Naomi Sugimura, Takahito Katano, Satoshi Tanida, Hiromi Kataoka, Makoto Sasaki   +13 more
doaj   +1 more source

Necrobiosis lipoidica of the breast associated with Crohn’s disease: a case report

Journal of Medical Case Reports, 2023
Background Necrobiosis lipoidica located to the breast; without evidence of glucose intolerance, is extremely rare, and its association to Crohn’s disease is not usual.
Awatef Kelati, François Durupt, Brigitte Balme   +2 more
doaj   +1 more source

Additional file 1: of Does the intestinal microbial community of Korean Crohnâ s disease patients differ from that of western patients?

, 2016
Table S1. Summary of Sequence Data of the Enrolled Samples. Table S2. Average Relative Abundance of Intestinal Microbiota at the Class and Family Levels. Table S3. Average Relative Abundance of Intestinal Microbiota at the Genus Level According to Clinical Disease Activity. Table S4. Taxonomic Comparison at the Class Level According to Disease Location
Eun, Chang, Kwak, Min-Jung, Han, Dong, Lee, A., Park, Dong, Yang, Suk-Kyun, Kim, Yong, Kim, Jihyun   +7 more
openaire   +1 more source

Lipidomic profiling in Crohn's disease: abnormalities in phosphatidylinositols, with preservation of ceramide, phosphatidylcholine and phosphatidylserine composition. [PDF]

, 2012
Crohn's disease is a chronic inflammatory condition largely affecting the terminal ileum and large bowel. A contributing cause is the failure of an adequate acute inflammatory response as a result of impaired secretion of pro-inflammatory cytokines by ...
Walker, Ann P., Hannun, Y.A., Bloom, SL, Walker, A.P., Sewell, GW, Segal, A.W., Koster, Grielof, Sewell, Gavin W., Hannun, Yusuf A., Koster, G, Vega, R., Bielawski, Jacek, Segal, Anthony W., Koster, G., Smith, P.J., Han, X., Rahman, FZ, Postle, AD, Goss, V., Vega, R, Hannun, YA, Postle, Anthony D., Rahman, Farooq Z., Bloom, Stuart L., Walker, AP, Han, X, Vega, Roser, Smith, Philip J., Smith, PJ, Rahman, F.Z., Bielawski, J, Bloom, S.L., Bielawski, J., Goss, V, Goss, Victoria, Han, Xianlin, Sewell, G.W., Segal, AW   +37 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

MOESM3 of Herb-partitioned moxibustion upregulated the expression of colonic epithelial tight junction-related proteins in Crohnâ s disease model rats

, 2016
Additional file 3. The ARRIVE guidelines.
Ji, Rong, Wang, Anqi, Shang, Haixia, Chen, Liu, Bao, Chunhui, Wu, Luyi, Wu, Huangan, Shi, Yin   +7 more
openaire   +1 more source

Clinical status, quality of life, and work productivity in Crohn's disease patients after one year of treatment with adalimumab [PDF]

, 2016
Objective: Clinical trials have shown the efficacy of adalimumab in Crohn’s disease, but the outcome in regular practice remains unknown. The aim of the study was to examine clinical status, quality of life, and work productivity of Crohn’s disease ...
Saro, C, de-Francisco, R, Lazaro, Pablo, de Francisco, Ruth, Ceballos, Daniel, Hernández, M, Fernández, LI, Muñoz, Fernando, de la Coba, Cristóbal, de-la-Coba, C, Aguilar, MD, Saro, Cristina, Garcia-Sanchez, Valle, Barrio, J, Aguilar, Maria Dolores, Lázaro, P, Barreiro-de-Acosta, M, Ceballos Santos, Daniel Sebastián, Fernandez, Luis I, Hernandez, Mariola, Muñoz, F, Barrio, Jesus, García-Sánchez, V, Barreiro-de Acosta, Manuel   +23 more
core   +1 more source

STAID: A Self‐Refining Deep Learning Framework for Spatial Cell‐Type Deconvolution with Biologically Informed Modeling

Advanced Science, EarlyView.
STAID is a unified deep learning framework that couples iterative pseudo‐spot refinement with neural network training through a feedback loop and exploits gene co‐expression information to model higher‐order interactions, achieving accurate and robust cell‐type deconvolution in spatial transcriptomics.
Jixin Liu, Shuli Sun, Zhengliang Lv, Xinyu Liu, Yihua Wang, Bingqiang Liu   +5 more
wiley   +1 more source

Esophageal Crohn's Disease Treated “Topically” with Swallowed Aerosolized Budesonide

Case Reports in Medicine, 2010
Proximal Crohn's disease, involving the esophagus, the stomach, the duodenum, and the proximal jejunum, is uncommon. Treatment for proximal Crohn's disease is based on data derived from case series than from controlled trials.
Petros Zezos, Georgios Kouklakis, Anastasia Oikonomou, Michail Pitiakoudis, Constantinos Simopoulos   +4 more
doaj   +1 more source