Results 101 to 110 of about 88,864 (219)

Nutritional and environmental determinants of maturation and disruption of the early life gut microbiome: A narrative review

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract The first 1000 days of life represent a critical window for gut microbiome assembly, with lifelong implications for child growth, immune development, and disease risk. This review synthesizes evidence on maternal, perinatal, and especially nutritional factors that influence early‐life intestinal colonization and highlights the consequences of ...
Carly Burow, Romy Shenderey, Fariha Chowdhury, Nyah Shah, Nikhil Pai   +4 more
wiley   +1 more source

Gut microbiome in pediatric acute pancreatitis and Crohn's disease versus irritable bowel syndrome and healthy controls

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Pediatric acute pancreatitis (AP), Crohn's disease (CD), and irritable bowel syndrome (IBS) are associated with gut dysbiosis, but differences and similarities between conditions are unknown. We hypothesized that gut microbial ecology would differ across these disorders. Methods Stool was collected from 120 subjects (AP [n = 30], CD
Neha R. Santucci, Chinenye R. Dike, Jenny Hellmann, Nicholas J. Ollberding, Qing Duan, Philip Minar, Lee A. Denson, David B. Haslam, Daniel Castillo, Maisam Abu‐El‐Haija   +9 more
wiley   +1 more source

Exclusive enteral nutrition containing transforming growth factor‐β improves intestinal barrier function in a colitis mouse model

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Exclusive enteral nutrition (EEN) is the first‐line treatment for pediatric Crohn's disease, but its mechanisms of action remain poorly understood. Our aim was to identify the mechanisms that could explain the anti‐inflammatory effects of EEN, studying the nutritional composition and transforming growth factor‐β (TGF‐β) effects, in ...
Kawthar Boumessid, Vickie Lacroix, Ekaterina Ovtchinnikova, Sophie Thenet, Marie Carriere, Frédérick Barreau, Emmanuel Mas   +6 more
wiley   +1 more source

Early‐life adverse events and risk of inflammatory bowel disease: A Scandinavian birth cohort study

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives The experience of childhood stressful or adverse life events is believed to imprint on immunological pathways and, therefore, might have lasting effects on inflammatory bowel disease (IBD) development. This study aimed to examine the association between experiences of early‐life adverse events and later IBD risk. Methods We followed
Ida Sigvardsson, Ketil Størdal, Henrik Imberg, Elisabeth Fernell, Christopher Gillberg, Johnny Ludvigsson, Karl Mårild   +6 more
wiley   +1 more source

Dual biologic therapy in inflammatory bowel disease, a retrospective cohort study of vedolizumab and anti‐tumor necrosis factor alpha therapy in children

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Despite advances in pediatric inflammatory bowel disease (PIBD) with biologics, remission rates remain at 47%–60% with loss‐of‐response rates at 60%–68%. Evidence for efficacy of dual biologic therapy (DBT) with anti‐tumor necrosis factor alpha therapy (anti‐TNF‐α)‐ vedolizumab (VDZ) for children refractory to anti‐TNF‐α therapy is ...
Jonathan E. M. O'Donnell, Carlie Bolles, Claire R. Reilly, Manal Morgan, Christopher Burgess, Fariha Balouch, Peter J. Lewindon   +6 more
wiley   +1 more source

Growth and development in paediatric onset inflammatory bowel disease: Data analysis from the CEDATA registry

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objective Different therapies may affect the growth and development of children and adolescents with inflammatory bowel disease (IBD) supporting specific therapy algorithms for paediatric Crohn's disease (CD) and ulcerative colitis (UC). Methods Growth and development data from the German–Austrian CEDATA‐GPGE registry entered between 2004 and ...
Ilse Broekaert, Anna Schmidt, Christoph Hünseler, Jan Delaffolie, CEDATA Study Group   +4 more
wiley   +1 more source

Anaemia in patients diagnosed with paediatric‐onset inflammatory bowel disease: A Danish nationwide cohort study

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Anaemia impairs daily activities and quality of life in patients with paediatric‐onset inflammatory bowel disease (PIBD). This study aimed to investigate the prevalence of anaemia at PIBD‐diagnosis and the following 5 years. Furthermore, anaemia subtypes and the association between anaemia and disease activity were assessed over ...
Julie Rahbek Norup, Sabine Jansson, Vibeke Wewer, Mikkel Malham   +3 more
wiley   +1 more source

Health Technology Assessment of Infliximab: A Rapid Review of Type 2 Studies

مجله دانشکده پزشکی اصفهان, 2012
Background: Infliximab has been used for treatment of patients with Crohn's disease whose symptoms or developed fistula could not be eliminated by standard treatments.
Mohamadreza Mobinizadeh, Alireza Oliyaeemanesh, Sheila Doaee, Mina Nejati, Parisa Aboee, Mahdi Azadbakht, Mahboubeh Valadkhani6   +6 more
doaj  

Exclusive enteral nutrition versus the Crohn's disease exclusion diet for remission induction in pediatric Crohn's disease: 52‐week study

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objective Nutritional therapy is a cornerstone for the induction of remission in pediatric Crohn's disease (CD); however, the optimal dietary strategy remains uncertain. This study aimed to compare the short‐ and long‐term therapeutic outcomes of exclusive enteral nutrition (EEN) and the Crohn's disease exclusion diet (CDED) in a large cohort ...
Danielle Pevzner, Adi Anafy, Hadar Moran‐Lev, Tut Galai, Achiya Amir, Shlomi Cohen, Tomer Ziv‐Baran, Anat Yersushalmy‐Feler   +7 more
wiley   +1 more source

Association of attention‐deficit/hyperactivity disorder and autism with inflammatory bowel disease activity

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives To estimate the effect of attention deficit hyperactivity disorder (ADHD) and autism on the disease activity of inflammatory bowel disease (IBD) in pediatric and young patients. Methods Patients diagnosed with IBD between the ages of 6 and 24 years were identified in Danish nationwide registries 1996–2022.
Sabine Jansson, Mads Damsgaard Wewer, Johan Burisch, Matthew P. Fox, Michael E. Benros, Charlotte Ulrikka Rask, Vibeke Wewer, Mikkel Malham   +7 more
wiley   +1 more source