Results 101 to 110 of about 162,990 (305)

Hepatic Glycogen Storage Diseases in Brazil: A Multicenter Study

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT To describe clinical and laboratory characteristics, emphasizing the evolution of patients with hepatic glycogen storage diseases (GSDs) followed in Brazilian reference centers. Multicenter, retrospective study involving 13 centers, using RedCap platform. 132 patients were included: 63 (47.8%) GSD type I (56 Ia, 7 Ib), 13 (9.8%) with type III (
Mariana Pena Costa   +23 more
wiley   +1 more source

Introduction to and Screening Visit Results of the Multicenter Pediatric Crohn's Disease Growth Study. [PDF]

open access: yes, 2020
BackgroundStatural growth impairment is more common in males with Crohn's disease (CD). We assessed sex differences in height Z score differences and bone age (BA) Z scores and characterized age of menarche in a novel contemporary cohort of pediatric CD ...
Andrews, Howard   +9 more
core  

NOD2 and inflammation: current insights [PDF]

open access: yes, 2018
The nucleotide-binding oligomerization domain (NOD) protein, NOD2, belonging to the intracellular NOD-like receptor family, detects conserved motifs in bacterial peptidoglycan and promotes their clearance through activation of a proinflammatory ...
Cucchiara, Salvatore   +3 more
core   +2 more sources

Additional file 1: of Circulating cathelicidin levels correlate with mucosal disease activity in ulcerative colitis, risk of intestinal stricture in Crohnâ s disease, and clinical prognosis in inflammatory bowel disease

open access: yes, 2017
Figure S1. Data analysis of UC clinical activity. Prevalence, sensitivity, specificity, PPV, NPV, and AUC values of ROC curves of LL-37 test alone, CRP test alone, and both in indicating (A) UC clinical remission and (B) moderate or severe UC clinical activity. (PDF 15 kb)
Tran, Diana   +13 more
openaire   +1 more source

Disease Remission: A Scoping Review With Thematic Analysis of the Scientific Literature With Implications for Chronic Rhinosinusitis

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Remission, a term used to describe a goal of treatment for some chronic diseases, has recently been proposed for chronic rhinosinusitis (CRS). However, it is unclear what remission means for CRS and why it should serve as a goal in the present‐day treatment of CRS.
Nikhil Parail   +7 more
wiley   +1 more source

Granuloma-Positive Crohn’s Disease

open access: yesCanadian Journal of Gastroenterology, 2007
BACKGROUND: The epithelioid granuloma is a characteristic histological feature of Crohn’s disease. In some pathological classification schemes, the criteria for a definite, probable or possible diagnosis have been listed, with the epithelioid granuloma ...
Hugh J Freeman
doaj   +1 more source

A screen of Crohn's disease-associated microbial metabolites identifies ascorbate as a novel metabolic inhibitor of activated human T cells. [PDF]

open access: yes, 2019
Microbial metabolites are an emerging class of mediators influencing CD4+ T-cell function. To advance the understanding of direct causal microbial factors contributing to Crohn's disease, we screened 139 predicted Crohn's disease-associated microbial ...
Borneman, James   +19 more
core   +1 more source

Multi‐omics data mining combined with experimental validation reveals ferroptosis‐ and autophagy‐associated hub genes as diagnostic candidates and immune modulators in atherosclerosis

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Using the GSE225650 dataset, we performed differential expression gene (DEG) screening, Weighted Gene Coexpression Network Analysis (WGCNA), and immune infiltration profiling on atherosclerosis (AS) samples, yielding 104 shared candidate genes. Subsequently, these 104 candidate genes were intersected with ferroptosis‑ and autophagy‑related gene sets ...
Xinou Zheng   +6 more
wiley   +1 more source

Additional file 4: of Circulating cathelicidin levels correlate with mucosal disease activity in ulcerative colitis, risk of intestinal stricture in Crohnâ s disease, and clinical prognosis in inflammatory bowel disease

open access: yes, 2017
Figure S4. Data analysis of CD clinical activity. Prevalence, sensitivity, specificity, PPV, NPV, and AUC values of ROC curves of LL-37 test alone, CRP test alone, and both in indicating (A) CD clinical remission and (B) moderate or severe CD clinical activity.
Tran, Diana   +13 more
openaire   +1 more source

Relapses, Comorbidities, and Predictors of Outcome in Anti‐GABAA Receptor Encephalitis

open access: yesAnnals of Neurology, EarlyView.
Objectives To characterize the magnetic resonance imaging (MRI) lesion dynamics, comorbidities, predictors of relapse, and outcomes in anti‐γ‐aminobutyric acid type A receptor (GABAAR) encephalitis, and assess the utility of LIM‐domain‐only‐protein 5 (LMO5) antibodies as tumor markers.
Claudia Papi   +33 more
wiley   +1 more source

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