Upadacitinib Induction and Maintenance Therapy for Crohn's Disease.
New England Journal of Medicine, 2023 BACKGROUND Upadacitinib, an oral selective Janus kinase (JAK) inhibitor, is under investigation for the treatment of Crohn's disease. METHODS In two phase 3 induction trials (U-EXCEL and U-EXCEED), we randomly assigned patients with moderate-to-severe ...
E. Loftus +18 more
semanticscholar +1 more source
Sweet's syndrome in a patient with Crohn's disease: a case report
Journal of Medical Case Reports, 2008 Background Sweet's syndrome, also known as acute febrile neutrophilic dermatosis, has been associated with malignancy, autoimmune disease and collagen vascular disease. The association of Crohn's disease and Sweet's syndrome is rare.
Mustafa Nadia M, Lavizzo Mark
doaj +1 more source
Elevated C-reactive protein in asymptomatic Crohn's disease patients. listen to the sound of silence [PDF]
, 2017 Bhattacharya et al1 confirmed and extended their previous finding2 indicating that “silent” Crohn’s disease (CD) patients (i.e., asymptomatic patients with elevated C-reactive protein [CRP] level) are a subgroup of patients at the higher risk of ...
CORLETO, Vito Domenico +3 more
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Anti-Saccharomyces cerevisiae antibodies in patients with inflammatory bowel disease and their first-degree relatives: Potential clinical value [PDF]
, 2002 Anti-Saccharomyces cerevisiae antibodies (ASCA) have been described as specific markers in Crohn's disease and their healthy first-degree relatives. 171 patients with Crohn's disease, their 105 first-degree relatives, 145 patients with ulcerative colitis
Folwaczny, Christian +5 more
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Canadian Journal of Gastroenterology and Hepatology, 2015 A series of clinical practice guidelines were recently developed by the Canadian Association of Gastroenterology (CAG) to provide clinicians with recommendations for the medical management of nonhospitalized ulcerative colitis (UC) patients.
A Hillary Steinhart, Aida Fernandes
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Arquivos de Gastroenterologia, 2014 Context and Objectives Focally enhanced gastritis and macrophage microaggregates are found in the upper gastrointestinal involvement of Crohn’s disease, and may reflect an underlying defective innate immunity.
Marcia Henriques de MAGALHÃES-COSTA +5 more
doaj +1 more source
Serum antibodies in first-degree relatives of patients with IBD: A marker of disease susceptibility? A follow-up pilot-study after 7 years [PDF]
, 2005 Introduction: Various disease-specific serum antibodies were described in patients with inflammatory bowel disease and their yet healthy first-degree relatives.
H.P. Török +29 more
core +4 more sources
Topical tacrolimus 0.1% ointment for treatment of cutaneous Crohn's Disease [PDF]
, 2013 Peer reviewedPublisher ...
El-Omar, Emad +4 more
core +2 more sources
Radiologic images of complications of Crohn's disease
International Journal of Gastrointestinal Intervention, 2023 Crohn's disease is a chronic inflammatory disease that may occur in the alimentary tract and has various clinical courses. It is characterized by several complications, including bowel strictures, bowel obstruction, fistulas, abscesses, and ...
Sungjin Yoon +2 more
doaj +1 more source
Azathioprine and 6-mercaptopurine for maintenance of surgically-induced remission in Crohn’s disease [PDF]
, 2014 Background Crohn’s disease (CD) is a chronic relapsing inflammatory condition. Many patients fail to achieve remission with medical management and require surgical interventions.
Angelberger +41 more
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