The Predictive Value of Periostin to Diagnose Crohn’s Disease
Background: There is still no sensitive and specific biomarker that can be used in the diagnosis and follow-up of Crohn’s disease, so we aimed to assess the diagnostic accuracy of serum periostin levels in Crohn’s disease.
Muharrem Keskin, Ali Topkaç
doaj +1 more source
Whereas typical Crohn’s disease is confined to the terminal ileum and presents with abdominal pain and diarrhea, gastroduodenal manifestations of Crohn’s disease are rare, with often asymptomatic patient presentations and inconclusive diagnostic testing.
Clive Jude Miranda +4 more
doaj +1 more source
Ileal and colonic Crohn's disease: Does location makes a difference in therapy efficacy?
Within the IBD entity of Crohn's disease, there is currently no differentiation between ileal and colonic manifestation for recruitment of patients in clinical trials, well-powered analysis of study results or therapeutic decisions in daily clinical ...
Raja Atreya +5 more
doaj +1 more source
PTGER4 expression-modulating polymorphisms in the 5p13.1 region predispose to Crohn's disease and affect NF-κB and XBP1 binding sites. [PDF]
Genome-wide association studies identified a PTGER4 expression-modulating region on chromosome 5p13.1 as Crohn's disease (CD) susceptibility region. The study aim was to test this association in a large cohort of patients with inflammatory bowel disease (
Achkar, Jean-Paul +14 more
core +9 more sources
The burden of inflammatory bowel disease (IBD) in Australia is increasing but national data about the current prevalence are limited. We aimed to estimate the prevalence of IBD (including Crohn's disease, ulcerative colitis and unspecified IBD) as well ...
Doreen Busingye +2 more
doaj +1 more source
The feasibility of wireless capsule endoscopy in detecting small intestinal pathology in children under the age of 8 years: a multicentre European study. [PDF]
Objective: To systematically evaluate the feasibility and methodology to carry out wireless capsule endoscopy (WCE) in children
Bufler, Philip +8 more
core +12 more sources
Association of IRGM gene mutations with inflammatory bowel disease in the Indian population. [PDF]
Mutations in the IRGM gene have been associated with Crohn's disease in several populations but have not been explored in Indian patients with this disease. This study examined the association of IRGM mutations with ulcerative colitis and Crohn's disease
Kirankumar Baskaran +2 more
doaj +1 more source
Detecting and managing small bowel Crohn’s disease – capsule endoscopy becoming a first line diagnostic method? [PDF]
Small bowel endoscopy is crucial for diagnosing small bowel Crohn’s disease, and capsule endoscopy is complemented by balloon-assisted enteroscopy to take biopsies and by magnetic resonance imaging to visualize enteral and extra-intestinal involvement ...
Albert, Jörg Gerhard +1 more
core +1 more source
Extraintestinal Crohn's disease (metastatic Crohn's disease)
Crohn's disease (CD) is an inflammatory bowel disorder that may involve any segment of the gastrointestinal tract from the oral cavity to the anus. CD belongs to the group of nonspecific inflammatory bowel diseases of unknown etiology.
Michał Rożalski
doaj +1 more source
Smoking in inflammatory bowel diseases: Good, bad or ugly? [PDF]
Smoking is an important environmental factor in inflammatory bowel disease (IBD), having different effects in ulcerative colitis (UC) and Crohn’s disease (CD).
Lakatos, László +2 more
core +1 more source

