Results 61 to 70 of about 180,947 (337)

Prediction of Perianal Fistula in Crohn’s Disease by Computed Tomography Enterography

The Turkish Journal of Gastroenterology
Background/Aims: The purpose of this study was to investigate whether computed tomography enterography can be used to predict the presence of perianal fistula in Crohn’s disease patients.
Genghuan Ni, Hongwei Zhao, Haiyan Shen, Senjuan Li, Weiqun Ao   +4 more
doaj   +1 more source

Additional file 11: of Genome analysis of E. coli isolated from Crohnâ s disease patients

, 2017
Bacteriocin production test in CD-associated strains. (DOC 42Â kb)
Rakitina, Daria, Manolov, Alexander, Kanygina, Alexandra, Garushyants, Sofya, Baikova, Julia, Alexeev, Dmitry, Ladygina, Valentina, Kostryukova, Elena, Larin, Andrei, Semashko, Tatiana, Karpova, Irina, Babenko, Vladislav, Ruzilya Ismagilova, Malanin, Sergei, Gelfand, Mikhail, Ilina, Elena, Gorodnichev, Roman, Lisitsyna, Eugenia, Aleshkin, Gennady, Scherbakov, Petr, Khalif, Igor, Shapina, Marina, Maev, Igor, Andreev, Dmitry, Govorun, Vadim   +24 more
openaire   +1 more source

ETV1 Drives CD4+ T Cell‐Mediated Intestinal Inflammation in Inflammatory Bowel Disease Through Amino Acid Transporter Slc7a5

Advanced Science, EarlyView.
This study identifies the transcription factor ETV1 as a key driver of CD4⁺ T cell‐mediated intestinal inflammation in inflammatory bowel disease (IBD). ETV1 promotes CD4⁺ T cell activation, proliferation, and Th17 differentiation by activating the amino acid transporter SLC7A5, fueling metabolic reprogramming.
Yan Shi, Song Wang, Yuqing Yan, Wei Chen, Yingying Cao, Dafan Chen, Wei Chen, Caiyun Ma, Xinjian Wan   +8 more
wiley   +1 more source

Environmental Factors in the Relapse and Recurrence of Inflammatory Bowel Disease:A Review of the Literature [PDF]

, 2015
The causes of relapse in patients with Crohn's disease (CD) and ulcerative colitis (UC) are largely unknown. This paper reviews the epidemiological and clinical data on how medications (non-steroidal anti-inflammatory drugs, estrogens and antibiotics ...
A Bitton, A Bitton, A Dignass, A Kaser, A Lunderquist, A Timmer, AJ Wakefield, AM Meyer, AN Ananthakrishnan, Andrew R. Hart, AP Dhillon, B Boye, BD Levy, C Abraham, C Luong, C Mowat, CN Bernstein, CS Guerreiro, CS North, D Lader, DA Gorard, DC Baumgart, DC Baumgart, E Lindberg, E Stepien, EA Magee, EA Magee, EA Miles, EF Foley, EM Sternberg, F Backhed, F Casellas, FN Aberra, G Bonizzi, G Bouma, G Cipolla, G Savoye, GE Reese, GF Bonner, GP Chrousos, H Brunner, H Tornqvist, IC Solberg, J Cosnes, J Cosnes, J Cosnes, J Eaden, JA Dominitz, JA Mancini, JB Felder, JC Meijers, JM Evans, KJ Khan, KS Rothfuss, L Beaugerie, L Beaugerie, L LeResche, L Lu, LM Lichtenberger, LR Sutherland, LR Sutherland, M Aslam, M Cottone, M Dybdahl, MB Grisham, MC Aldhous, MC Pitcher, MN Merrett, MT Severinsen, NJ Simmonds, NP Thompson, O Hovde, OA Hatoum, P Seksik, PJ Loll, R Reid, R Schreck, RD Cohen, RK Linskens, RM Beattie, RS Barua, S Danese, S Hayashi, S Levenstein, S Parcell, S Sigaud, S Singh, S Zhang, Simon S. M. Chan, SL Jowett, SM Collins, SM Collins, SS Hecht, ST Smale, SU Christl, SV Kane, T Hisamatsu, THJ Florin, Thomas D. Martin, U Erikson   +99 more
core   +1 more source

Meckel's Diverticulum in Crohn's Disease

Canadian Journal of Gastroenterology, 2001
Meckel's diverticulum is a congenital abnormality of the distal ileum associated with failed vitelline duct closure. Detailed pathological studies have estimated its frequency to be about 2% of the general population, and it has been anecdotally recorded
Hugh J Freeman
doaj   +1 more source

Additional file 9: of Genome analysis of E. coli isolated from Crohnâ s disease patients

, 2017
Test of non randomness of the operon enrichment. (DOC 871Â kb)
Rakitina, Daria, Manolov, Alexander, Kanygina, Alexandra, Garushyants, Sofya, Baikova, Julia, Alexeev, Dmitry, Ladygina, Valentina, Kostryukova, Elena, Larin, Andrei, Semashko, Tatiana, Karpova, Irina, Babenko, Vladislav, Ruzilya Ismagilova, Malanin, Sergei, Gelfand, Mikhail, Ilina, Elena, Gorodnichev, Roman, Lisitsyna, Eugenia, Aleshkin, Gennady, Scherbakov, Petr, Khalif, Igor, Shapina, Marina, Maev, Igor, Andreev, Dmitry, Govorun, Vadim   +24 more
openaire   +1 more source

Genetically‐Programmed Hypervesiculation of Lactiplantibacillus Plantarum Increases Production of Bacterial Extracellular Vesicles with Therapeutic Efficacy in a Preclinical Inflammatory Bowel Disease Model

Advanced Science, EarlyView.
The development of a novel engineered strain of Lactiplantibacillus plantarum (Lp) is reported that can produce bacterial extracellular vesicles (BEVs) at >60‐fold higher yields than the unmodified parental strain. These Lp BEVs retain therapeutic bioactivity as validated in a mouse model of dextran sodium sulfate‐induced colitis.
Nicholas H Pirolli, Daniel Levy, Alyssa Schledwitz, Natalia Sampaio Moura, Mitali Sarkar, Talia J. Solomon, Emily H. Powsner, Raith Nowak, Zuzanna Mamczarz, Christopher J. Bridgeman, Sulayman Khan, Andrew Hui, Nidhi Anne, Laura Reus, William E. Bentley, Jean‐Pierre Raufman, Steven M. Jay   +16 more
wiley   +1 more source

Additional file 12: of Genome analysis of E. coli isolated from Crohnâ s disease patients

, 2017
Competition co-culture of CD-E. coli and isolates from healthy individuals. (DOC 56Â kb)
Rakitina, Daria, Manolov, Alexander, Kanygina, Alexandra, Garushyants, Sofya, Baikova, Julia, Alexeev, Dmitry, Ladygina, Valentina, Kostryukova, Elena, Larin, Andrei, Semashko, Tatiana, Karpova, Irina, Babenko, Vladislav, Ruzilya Ismagilova, Malanin, Sergei, Gelfand, Mikhail, Ilina, Elena, Gorodnichev, Roman, Lisitsyna, Eugenia, Aleshkin, Gennady, Scherbakov, Petr, Khalif, Igor, Shapina, Marina, Maev, Igor, Andreev, Dmitry, Govorun, Vadim   +24 more
openaire   +1 more source

Intestinal Neutral Ceramidase Deficiency Triggers Regulatory T Cell Response via Gd3 to Protect the Host from Intestinal Inflammation

Advanced Science, EarlyView.
Deletion of ASAH2 in intestinal epithelial cells induces the accumulation of ganglioside GD3 via regulating ST8SIA1. GD3 is identified as the glycolipid ligand for the inhibitory receptor Siglec‐E on macrophages. GD3/Siglec‐E ligation polarizes macrophages and promotes the proliferation of colonic ST2+ T regulatory cells via the induction of IL‐33. The
Zhishan Xu, Chao Lei, Mukesh K Sriwastva, Ting Wang, Amanguli Tuohongerbieke, Xiaotong Song, Collin Noud, Shannon Derkson, Yi Tan, Gerald Dryden, Craig J McClain, Zhongbin Deng   +11 more
wiley   +1 more source

Esophageal Crohn's Disease Treated “Topically” with Swallowed Aerosolized Budesonide

Case Reports in Medicine, 2010
Proximal Crohn's disease, involving the esophagus, the stomach, the duodenum, and the proximal jejunum, is uncommon. Treatment for proximal Crohn's disease is based on data derived from case series than from controlled trials.
Petros Zezos, Georgios Kouklakis, Anastasia Oikonomou, Michail Pitiakoudis, Constantinos Simopoulos   +4 more
doaj   +1 more source