Results 61 to 70 of about 9,364,795 (319)

Meckel's Diverticulum in Crohn's Disease

Canadian Journal of Gastroenterology, 2001
Meckel's diverticulum is a congenital abnormality of the distal ileum associated with failed vitelline duct closure. Detailed pathological studies have estimated its frequency to be about 2% of the general population, and it has been anecdotally recorded
Hugh J Freeman
doaj   +1 more source

Diagnosis and outcome of oesophageal Crohn's disease [PDF]

, 2019
BACKGROUND AND AIMS: Crohn's disease (CD) can involve any part of the gastrointestinal tract. We aimed to characterize clinical, endoscopic, histologic features and treatment outcomes of CD patients with oesophageal involvement.
Beaton, D, Chaparro, M, Ellul, P, Katsanos, K, Oliveira, AM, et al., Rodrigues, R, Savarino, E, Sladek, M, Teich, N, van der Woude, J, Vavricka, R, Wei, J   +11 more
core   +1 more source

A comprehensive metabolite fingerprint of fibrostenosis in patients with Crohn’s disease [PDF]

, 2023
Simon Bos, Triana Lobatón, Martine De Vos, Sophie Van Welden, Vera Plekhova, Ellen De Paepe, Lynn Vanhaecke, Debby Laukens   +7 more
openalex   +1 more source

The safety of vedolizumab for ulcerative colitis and Crohn's disease

Gut, 2016
Objective Vedolizumab is a gut-selective antibody to α4β7 integrin for the treatment of ulcerative colitis (UC) and Crohn's disease (CD). We report an integrated summary of the safety of vedolizumab.
J. Colombel, B. Sands, P. Rutgeerts, W. Sandborn, S. Danese, G. D'Haens, R. Panaccione, E. Loftus, S. Sankoh, I. Fox, A. Parikh, C. Milch, B. Abhyankar, B. Feagan   +13 more
semanticscholar   +1 more source

Wireless Capsule Device for Targeted and Safe Tissue Biopsy with Integrated Sensing

Advanced Materials Technologies, EarlyView.
This work presents a capsule device featuring a novel magnetically controlled biopsy mechanism for enhanced safety. The biopsy unit integrates a foldable linkage with dual magnets, creating a magnetic attraction–based safeguard, preventing unintended activation during locomotion. A flexible sensor provides real‐time penetration displacement sensing for
Kiyoung Kim, Jacob Katona, Jiale Chu, Boyang Xiao, Rishi Naik, Xiaoguang Dong   +5 more
wiley   +1 more source

Introduction to and Screening Visit Results of the Multicenter Pediatric Crohn's Disease Growth Study. [PDF]

, 2020
BackgroundStatural growth impairment is more common in males with Crohn's disease (CD). We assessed sex differences in height Z score differences and bone age (BA) Z scores and characterized age of menarche in a novel contemporary cohort of pediatric CD ...
Andrews, Howard, Gokhale, Ranjana, Goyal, Alka, Gupta, Neera, Guthery, Stephen, Keljo, David, Leu, Cheng-Shiun, Lustig, Robert H, Patel, Ashish S, Sylvester, Francisco   +9 more
core  

A Systematic Approach to Analyze T Cell Migration: Application to Mouse Melanoma Tumors

Advanced Therapeutics, EarlyView.
The results show that a minimum of two migration speeds can be rigorously identified from the data with cells switching between a fast, persistent migratory state, and a slow, random migration state. These results will help in identifying genetic factors that influence rapid migration, among other applications, such as quality control for CAR‐T cell ...
Nikolaos Memmos, Jason S. Mitchell, Brian T. Fife, David Masopust, David J. Odde   +4 more
wiley   +1 more source

Esophageal Crohn's Disease Treated “Topically” with Swallowed Aerosolized Budesonide

Case Reports in Medicine, 2010
Proximal Crohn's disease, involving the esophagus, the stomach, the duodenum, and the proximal jejunum, is uncommon. Treatment for proximal Crohn's disease is based on data derived from case series than from controlled trials.
Petros Zezos, Georgios Kouklakis, Anastasia Oikonomou, Michail Pitiakoudis, Constantinos Simopoulos   +4 more
doaj   +1 more source

Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy [PDF]

, 2006
Background: Progressive multifocal leukoencephalopathy (PML) was reported to have developed in three patients treated with natalizumab. We conducted an evaluation to determine whether PML had developed in any other treated patients.
Barkhof, F., Clifford, D.B., Curfman, B., Fahle, G., Fischer, S., Habil, M., Hou, J., Jäger, H.R., Major, E.O., Miszkiel, K., Mueller-Lenke, N., Radue, E.-W., Ryschkewitsch, C., Sanchez, E., Yousry, T.A.   +14 more
core   +1 more source

Single‐Cell Transcriptomics Unravels Growth Factor Erv1‐Like Mediated Ferroptosis as a Key Driver of Intestinal Epithelial Dysfunction in Ulcerative Colitis

Advanced Science, EarlyView.
Single‐cell transcriptomic profiling of ulcerative colitis (UC) tissues identified downregulation of GFER in intestinal epithelial cells. Mechanistically, GFER interacts with PCBP1 to help maintain intracellular iron homeostasis and may also reduce lipid peroxidation by activating the PGC‐1α/PPARγ signaling pathway, thereby inhibiting ferroptosis ...
Ya Song, Fangyan Tan, Qian Song, Xiaohui Liao, Zhechuan Mei, Lin Lv   +5 more
wiley   +1 more source