Results 71 to 80 of about 181,689 (337)

Toll-like receptor 4 and NOD2/CARD15 mutations in Hungarian patients with Crohn's disease: Phenotype-genotype correlations [PDF]

open access: yes, 2005
AIM: To determine common NOD2/CARD15 mutations and TLR4 D299G polymorphism in Hungarian patients with CD. METHODS: A total of 527 unrelated patients with CD (male/female: 265/262, age: 37.1 (SD 7.6) years) and 200 healthy subjects were included.
Altorjay, István   +12 more
core   +1 more source

Correlation Between Fecal Microbiota and Corticosteroid Responsiveness in Primary Immune Thrombocytopenia: an Exploratory Study

open access: yesAdvanced Science, EarlyView.
This study uses gut microbiome data to predict corticosteroid response in patients with immune thrombocytopenia (ITP). Fecal samples from 212 patients with ITP are sequenced. Six machine‐learning algorithms are used to train predictive models. The support vector machine‐based model integrated clinical data and selected microbial species, diversities ...
Feng‐Qi Liu   +38 more
wiley   +1 more source

Edwardsiella tarda Infection Triggering Acute Relapse in Pediatric Crohn’s Disease

open access: yesCase Reports in Infectious Diseases, 2019
Crohn’s disease exacerbations can often be associated with bacterial infections causing gastroenteritis. We report a child who experienced exacerbation of his Crohn’s disease associated with a positive stool culture for Edwardsiella tarda (E.
A. K. Li   +3 more
doaj   +1 more source

Chronotype and Sleep Quality in Patients with Inflammatory Bowel Disease

open access: yesHaseki Tıp Bülteni, 2020
Aim:Chronotype and sleep disturbance are both considered risk factors for chronic autoimmune diseases. However, there is lack of knowledge with respect to chronic inflammatory bowel disease and chronotype patterns.
Elmas Biberci Keskin   +1 more
doaj   +1 more source

Psychosocial problems experienced by patients depending on Crohn’s disease activity: an exploratory study

open access: yesHealth Psychology Report, 2021
Introduction The aim of the study was to assess the effect of Crohn’s disease (CD) activity and factors such as having a job, a family, or a partner on the severity of psychosocial problems experienced by them.
Wojciech Otrębski, Monika Krupa-Nowosad
doaj   +1 more source

Crohn\u27s Disease [PDF]

open access: yes, 2018
Crohn’s disease is a progressive and systemic autoimmune disease that causes inflammation to any part of the gastrointestinal tract. The inflammation causes some of the clinical manifestations of crohn’s disease such as abdominal pain, diarrhea ...
Hubena, Mergithu
core   +1 more source

The role of the novel Th17 cytokine IL-26 in intestinal inflammation [PDF]

open access: yes, 2009
Background and aims: Interleukin 26 (IL-26), a novel IL-10-like cytokine without a murine homologue, is expressed in T helper 1 (Th1) and Th17 cells. Currently, its function in human disease is completely unknown. The aim of this study was to analyse its
Auernhammer, Christoph J.   +7 more
core   +1 more source

Implantable Self‐Powered Systems for Electrical Stimulation Medical Devices

open access: yesAdvanced Science, EarlyView.
In this paper, the design strategy and clinical application of ISS are discussed in depth from four aspects: the design and optimization of the energy collection module, the selection and preparation of adaptive electrode materials, the innovation of system design strategy, and the biological effect of electrical stimulation of ISS.
Xi Cui, Li Wu, Chao Zhang, Zhou Li
wiley   +1 more source

Clinical variables related to small bowel obstruction: comparison of patients with and without Crohn’s disease

open access: yesGastroenterology Insights, 2012
Small bowel obstruction is a known complication of Crohn’s disease. Determining need for operation is a demanding task. The aim of this study was to fine tune the decision-making process by evaluating standard clinical and laboratory parameters in small ...
Awad Al Qahtani   +3 more
doaj   +1 more source

AhR‐Dependent Induction of β‐Defensin 1 in Colonic Epithelial Cells Regulates Cross‐Talk between Gut Microbiota and Immune Response Leading to Attenuation of Colitis

open access: yesAdvanced Science, EarlyView.
This study identifies a key signaling pathway involving the environmental sensor AhR and antimicrobial peptides, such as BD‐1, in the regulation of intestinal homeostasis. It highlights the role of BD‐1 in regulating gut microbiota and the intestinal immune response.
Manikandan Palrasu   +16 more
wiley   +1 more source

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