Aretaeus of Cappadocia (1st century CE) describeda young man with chronic and recurring abdominaldistress possibly representing the first recorded instanceof Crohn disease (CD).1-3 More evidence that this diseasewas extant for many years comes from the ...
Campos, Fernando Peixoto Ferraz de+1 more
core +4 more sources
Early bronchopulmonary involvement in Crohn disease: a case report [PDF]
BACKGROUND: Bronchopulmonary manifestations of Crohn disease have been rarely described in children, including both subclinical pulmonary involvement and severe lung disease.
A Bitton+21 more
core +5 more sources
Crohn's disease or Crohn's diseases? [PDF]
Disease behaviour in Crohn’s disease is dynamic and not stable over time In their landmark paper of 1932, Crohn, Ginzburg, and Oppenheimer1 described “a disease of the terminal ileum, affecting mainly young adults and characterised by a subacute or chronic necrotising and cicratrising inflammation.
Arnott, IDR, Satsangi, J
openaire +4 more sources
EMM: Coloproctology presents the state-of-the-art in coloproctology. The topics covered include anatomy, physiology, anal disorders, dermatology, functional disorders, inflammatory bowel disease, b ...
Gunnar Järnerot, Rune Sjödahl
openaire +5 more sources
In situ PCR for Mycobacterium tuberculosis in endoscopic mucosal biopsy specimens of intestinal tuberculosis and Crohn disease [PDF]
Tuberculosis and Crohn disease are granulomatous disorders affecting the intestinal tract with similar clinical manifestations and pathologic features.
Donoghue, HD+3 more
core +1 more source
Metagenomic Analysis of the Structure and Function of the Human Gut Microbiota in Crohn's Disease [PDF]
Inflammatory bowel diseases (IBD), such as Crohn’s disease, are chronic, immunologically mediated disorders that have severe medical consequences.
Claire M. Fraser-Liggett
core +2 more sources
Panenteric capsule endoscopy identifies proximal small bowel disease guiding upstaging and treatment intensification in Crohn’s disease: A European multicentre observational cohort study [PDF]
Background: Endoscopically defined mucosal healing in Crohn\u2019s disease is associated with improved outcomes. Panenteric capsule endoscopy enables a single non-invasive assessment of small and large bowel mucosal inflammation.
A. Elosua+12 more
core +3 more sources
Quantitative Assessment of the Impact of Crohn\u27s Disease on Protein Abundance of Human Intestinal Drug-Metabolising Enzymes and Transporters [PDF]
Crohn\u27s disease affects the mucosal layer of the intestine, predominantly ileum and colon segments, with the potential to affect the expression of intestinal enzymes and transporters, and consequently, oral drug bioavailability.
Achour, Brahim+4 more
core +3 more sources
The first joint ESGAR/ ESPR consensus statement on the technical performance of cross-sectional small bowel and colonic imaging [PDF]
Objectives: To develop guidelines describing a standardised approach to patient preparation and acquisition protocols for magnetic resonance imaging (MRI), computed tomography (CT) and ultrasound (US) of the small bowel and colon, with an emphasis on ...
Avni, F.+14 more
core +2 more sources
Edwardsiella tarda Infection Triggering Acute Relapse in Pediatric Crohn’s Disease [PDF]
Crohn\u27s disease exacerbations can often be associated with bacterial infections causing gastroenteritis. We report a child who experienced exacerbation of his Crohn\u27s disease associated with a positive stool culture ...
Ashok, D+3 more
core +2 more sources