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Aretaeus of Cappadocia (1st century CE) described a young man with chronic and recurring abdominal distress possibly representing the first recorded instance of Crohn disease (CD).1-3 More evidence that this disease was extant for many years comes from ...
Stephen A. Geller+1 more
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Early bronchopulmonary involvement in Crohn disease: a case report [PDF]
Background Bronchopulmonary manifestations of Crohn disease have been rarely described in children, including both subclinical pulmonary involvement and severe lung disease.
Braggion Cesare+5 more
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Leukocytoclastic Vasculitis in a Patient With Crohn Disease: A Case Report [PDF]
Leukocytoclastic vasculitis (LCV) is an idiopathic small vessel vasculitis. Leukocytoclastic vasculitis can be found in a spectrum of diseases and is noted as a rare extraintestinal manifestation of Crohn disease.
Mark Daniele Bugada BS+1 more
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Application of enterostomy in surgical treatment of Crohn disease [PDF]
Crohn disease is a chronic inflammatory disease characterized by segmental transmural inflammation of the gastrointestinal tract. The primary treatment for Crohn disease is medication, but as the disease progresses, complications such as obstruction ...
Song-Lin WAN, Zhao DING, Qun QIAN
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Crohn’s Disease of the Vulva: a Case Report [PDF]
Crohn’s disease is a multi-systemic chronic inflammatory disease that can affect various organs besides the gastrointestinal tract such as joints, uvea, and the skin.
Kalliopi Kokkali+7 more
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Crohn's disease or Crohn's diseases? [PDF]
Disease behaviour in Crohn’s disease is dynamic and not stable over time In their landmark paper of 1932, Crohn, Ginzburg, and Oppenheimer1 described “a disease of the terminal ileum, affecting mainly young adults and characterised by a subacute or chronic necrotising and cicratrising inflammation.
Arnott, IDR, Satsangi, J
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Approaches in the treatment of perianal fistula in Crohn disease
Perianal fistula is a common complication of Crohn disease, and it is a great burden on the life and psychology of patients, but its treatment is still a difficult problem to face.
Rui Li
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Abstract Understanding the aetiology and pathogenesis of Crohn's disease remains a challenge, but it is clearly an interaction between the environment and a genetically susceptible individual. Multiple genes are being described, each contributing a small degree of susceptibility or protection, but the functional consequences of gene mutations are not ...
Gunnar Järnerot, Rune Sjödahl
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Extraintestinal Crohn's disease (metastatic Crohn's disease)
Crohn's disease (CD) is an inflammatory bowel disorder that may involve any segment of the gastrointestinal tract from the oral cavity to the anus. CD belongs to the group of nonspecific inflammatory bowel diseases of unknown etiology.
Michał Rożalski
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Crohn disease is associated with nonnecrotizing epithelioid granulomas, which rarely involve extra-intestinal solid organs. Management of moderate-to-severe Crohn disease, especially with extra-intestinal manifestations, relies on biologic therapies and ...
Collin Mayemura+5 more
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