LRH-1 mitigates intestinal inflammatory disease by maintaining epithelial homeostasis and cell survival. [PDF]
, 2018 Epithelial dysfunction and crypt destruction are defining features of inflammatory bowel disease (IBD). However, current IBD therapies targeting epithelial dysfunction are lacking.
Bayrer, James R +8 more
core +2 more sources
Clinical Medicine Insights: Case Reports, 2017 Crohn disease is an immune-mediated inflammatory condition with gastrointestinal and extraintestinal manifestations in patients. Pulmonary involvement of Crohn disease is one manifestation.
Taufiq Zaman +2 more
doaj +1 more source
The first joint ESGAR/ ESPR consensus statement on the technical performance of cross-sectional small bowel and colonic imaging [PDF]
, 2016 Objectives: To develop guidelines describing a standardised approach to patient preparation and acquisition protocols for magnetic resonance imaging (MRI), computed tomography (CT) and ultrasound (US) of the small bowel and colon, with an emphasis on ...
Avni, F. +14 more
core +2 more sources
Assessing the inflammatory severity of the terminal ileum in Crohn disease using radiomics based on MRI [PDF]
, 2022 Honglei Ding +9 more
openalex +3 more sources
Efficacy of adalimumab as second-line therapy in a pediatric cohort of crohn’s disease patients who failed infliximab therapy: The Italian society of pediatric gastroenterology, hepatology, and nutrition experience [PDF]
, 2019 Background: Adalimumab (Ada) treatment is an available option for pediatric Crohn’s disease (CD) and the published experience as rescue therapy is limited.
Accomando S. +15 more
core +1 more source
Anorexia Nervosa Complicating Pediatric Crohn Disease—Case Report and Literature Review
Frontiers in Pediatrics, 2018 Crohn disease and anorexia nervosa share common symptoms of weight loss and reduced oral intake. The prevalence of both disorders has increased over time.
Aedin Collins +7 more
doaj +1 more source
Identification of low-frequency TRAF3IP2 coding variants in psoriatic arthritis patients and functional characterization [PDF]
, 2012 Introduction: In recent genome-wide association studies for psoriatic arthritis (PsA) and psoriasis vulgaris, common coding variants in the TRAF3IP2 gene were identified to contribute to susceptibility to both disease entities.
Apel, Maria +6 more
core +2 more sources
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, EarlyView.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
The Saudi Journal of Gastroenterology, 2014 Background/Aims: Despite the remarkable increase in the incidence of Crohn′s disease among Saudis in recent years, data about Crohn′s disease in Saudi Arabia are scarce.
Abdulrahman M. Aljebreen +5 more
doaj +1 more source
Advanced Functional Materials, EarlyView.Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz +3 more
wiley +1 more source