Results 71 to 80 of about 9,352,293 (347)
A specific gene-microbe interaction drives the development of Crohn’s disease–like colitis in mice
Science immunology, 2019 Combined deficiency of NOD2 and NAPDH oxidase triggers Crohn’s-like disease driven by a mouse pathobiont, Mucispirillum. A mouse model for Crohn’s disease Although several mouse models of inflammatory bowel disease exist, Crohn’s disease has been ...
Roberta Caruso +6 more
semanticscholar +1 more source
Advanced NanoBiomed Research, EarlyView.This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley +1 more source
Simultaneous central retinal artery occlusion and optic nerve vasculitis in Crohn disease
American Journal of Ophthalmology Case Reports, 2017 Purpose: To describe a case of Crohn disease presenting as occlusive vasculitis resulting in a central retinal artery occlusion (CRAO) in one eye and transient ischemic optic neuropathy in the fellow eye.
Razek Georges Coussa +4 more
doaj +1 more source
Blood-Derived DNA Methylation Signatures of Crohn's Disease and Severity of Intestinal Inflammation.
Gastroenterology, 2019 BACKGROUND & AIMS Crohn's disease is a relapsing and remitting inflammatory disorder with a variable clinical course. Although most patients present with an inflammatory phenotype (B1), approximately 20% of patients rapidly progress to complicated ...
Hari Somineni +28 more
semanticscholar +1 more source
Advanced NanoBiomed Research, EarlyView.This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari +5 more
wiley +1 more source
Biologics: Targets & Therapy, 2008 David A SchwartzVanderbilt University Medical Center, Nashville, TN, USAContext: Certolizumab pegol (CDP 870) is a new anti-tumor necrosis factor (TNF) therapy currently in development for the treatment of Crohn’s disease, rheumatoid arthritis,
David A Schwartz
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Animal Research and One Health, EarlyView.Selenomethionine can ameliorate arachidonic acid‐induced colonic injury through synergistic mechanisms, including alleviating inflammatory responses, improving barrier integrity, enhancing antioxidant capacity by upregulating selenoprotein expression, selectively regulating AA metabolism to reduce pro‐inflammatory oxylipins and promote the production ...
Huihui Tian +8 more
wiley +1 more source
The Saudi Journal of Gastroenterology, 2009 Distinguishing tuberculosis and Crohn′s disease in patients presenting with chronic abdominal pain and diarrhea is a huge diagnostic challenge, particularly in tuberculosis endemic countries.
Navaneethan Udayakumar +3 more
doaj
Arthritis &Rheumatology, EarlyView.Objective We evaluated serious infection risk in offspring exposed to tumor necrosis factor inhibitors (TNFi) in utero, separated by TNFi timing and placental transfer ability. Methods Using MarketScan (2011–2021), we identified offspring born to mothers with chronic inflammatory diseases.
Leah K. Flatman +6 more
wiley +1 more source
Diagnosis of regional enrteritis (Crohn disease)
The Saudi Journal of Gastroenterology, 2003 Regional enteritis (Crohn disease) may present a diagnostic problem that needs to be solved by clinicians practicing in areas known to be endemic for tuberculosis.
Khalil Mohamed
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