Results 71 to 80 of about 59,318 (349)

Reoperative pouch surgery for suspected Crohn's‐related complications aided by biologic coverage: Early experience from an inflammatory bowel disease center

Annals of Gastroenterological Surgery, EarlyView.
This paper demonstrates that revisional/redo ileal pouch anal anastomosis (IPAA) surgery with concurrent biologic therapy provides a viable, stoma‐free alternative for patients with Crohn's disease‐like complications, showing a high functioning pouch rate and expanding options for managing pouch failure.
Mehmet Gulmez, Daniel J. Wong, Ariela K. Holmer, Eren Esen, Shannon Chang, Arman Erkan, David Hudesman, Andre da Luz Moreira, Feza H. Remzi   +8 more
wiley   +1 more source

Identification of low-frequency TRAF3IP2 coding variants in psoriatic arthritis patients and functional characterization [PDF]

, 2012
Introduction: In recent genome-wide association studies for psoriatic arthritis (PsA) and psoriasis vulgaris, common coding variants in the TRAF3IP2 gene were identified to contribute to susceptibility to both disease entities.
Apel, Maria, Behrens, Frank, Burkhardt, Harald, Böhm, Beate B., Hüffmeier, Ulrike, Reis, André, Uebe, Steffen   +6 more
core   +2 more sources

Clinical and Economic Insights Into Surgery for Colonic Diverticular Perforation: A Long‐Term Observational Cohort Study

Annals of Gastroenterological Surgery, EarlyView.
The sigmoid colon was the most common perforation site among patients with colonic diverticular perforation. The patients' conditions, length of hospital stay, and hospitalization cost were significantly worse in left‐sided colon diverticular perforation than in right‐sided colon diverticular perforation. The clinical characteristics differed according
Minoru Fujita, Noriaki Manabe, Munenori Takaoka, Masaharu Higashida, Hideo Matsumoto, Atsushi Urakami, Tomoki Yamatsuji, Tomio Ueno, Jiro Hata, Ken Haruma, Collaborators, Hisako Kubota, Jiro Hayashi, Masaki Matsubara, Takako Konishi, Emiko Bukeo, Tomohiro Tanikawa, Jun Nakamura, Mitsuhiko Suehiro, Maki Ayaki, Takahisa Murao, Kazuhiro Yoshida, Takashi Akiyama, Katsuya Kato, Hirofumi Kawamoto, Tomoari Kamada, Akiko Shiotani, Minoru Haisa, Yoshio Naomoto, Toshihiro Hirai   +29 more
wiley   +1 more source

Prognostic Value of Serum Insulin‐Like Growth Factor‐1 in Patients With Anal Fistula Treated by Incision‐Thread‐Drawing Surgery

Annals of Gastroenterological Surgery, EarlyView.
IGF‐1 levels above 174.9 ng/mL were associated with better wound healing and lower postoperative inflammation. Higher IGF‐1 levels correlated with improved anal function at 7 and 14 days post‐surgery. ABSTRACT Background Anal fistula is a chronic condition characterized by an abnormal tract between the anal canal and perianal skin, often leading to ...
Zhijun Wu, Xuexue Yin, Jing Li
wiley   +1 more source

Patient-derived Colonoids From Disease-spared Tissue Retain Inflammatory Bowel Disease-specific Transcriptomic Signatures

Gastro Hep Advances, 2023
Background and Aims: A key histopathological feature of inflammatory bowel disease is damage to the mucosa, including breakdown of the epithelial barrier.
Tatiana A. Karakasheva, Yusen Zhou, Hongbo M. Xie, Gloria E. Soto, Tiana D. Johnson, Madison A. Stoltz, Daana M. Roach, Noor Nema, Chizoba N. Umeweni, Kaitlyn Naughton, Lauren Dolinsky, James A. Pippin, Andrew D. Wells, Struan F.A. Grant, Louis Ghanem, Natalie Terry, Amanda B. Muir, Kathryn E. Hamilton   +17 more
doaj  

The impact of exclusive enteral nutrition on the intestinal microbiota in inflammatory bowel disease

AIMS Microbiology, 2018
It is increasingly clear that the intestinal microbiota plays key roles in the pathogenesis of the conditions known as Crohn disease and ulcerative colitis (jointly known as the inflammatory bowel diseases).
Andrew S Day
doaj   +1 more source

Thiopurines are negatively associated with anthropometric parameters in pediatric Crohn's disease. [PDF]

, 2018
AimTo determine the distribution of anthropometric parameter (AP)-z-scores and characterize associations between medications/serum biomarkers and AP-z-scores in pediatric Crohn's disease (CD).MethodsCD patients [< chronological age (CA) 21 years] were
Andrews, Howard, Chao, Cewin, Gupta, Neera, Leu, Cheng-Shiun, Lustig, Robert H, Vittinghoff, Eric   +5 more
core   +1 more source

Characterizing the Healthcare Utilization and Costs of Hereditary Hemorrhagic Telangiectasia

American Journal of Hematology, EarlyView.
ABSTRACT Hereditary hemorrhagic telangiectasia (HHT) is the second‐most common inherited bleeding disorder worldwide, afflicting one in 4000–5000 people, and is the most morbid inherited bleeding disorder of women. HHT causes recurrent severe epistaxis, chronic gastrointestinal bleeding, heavy menstrual bleeding, and arteriovenous malformations in the ...
Hanny Al‐Samkari, Tracy J. Mayne, Misty Troutt, Hemant Patle, Marianne Clancy, Eric Duhaime   +5 more
wiley   +1 more source

Understanding the health and social care needs of people living with IBD: A meta-synthesis of the evidence [PDF]

, 2012
AIM: To undertake a metasynthesis of qualitative studies to understand the health and social needs of people living with inflammatory bowel disease (IBD).
Griffiths, Jane, Kemp, Karen, Lovell, Karina   +2 more
core   +1 more source

Exploring Oral Health Related Quality of Life in Rett Syndrome Using Directed Content Analysis

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT No validated oral health‐related quality of life (OHRQOL) instrument currently exists for those with severe intellectual and developmental disabilities and who communicate non‐verbally. This qualitative study aimed to explore the domains that were important to the oral health‐related quality of life in individuals with Rett syndrome (RTT).
Yvonne Yee Lok Lai, Jenny Anne Downs, Helen Margaret Leonard, Laurence James Walsh, Sobia Zafar   +4 more
wiley   +1 more source