Results 81 to 90 of about 59,318 (349)

Fungal dysbiosis predicts the diagnosis of pediatric Crohn's disease [PDF]

open access: yes, 2018
AIM: To investigate the accuracy of fungal dysbiosis in mucosa and stool for predicting the diagnosis of Crohn’s disease (CD). METHODS: Children were prospectively enrolled in two medical centers: one university hospital and one private gastroenterology ...
Al Barrag, Ahmad M.   +8 more
core   +1 more source

The Behavioral Phenotype and Importance of Multidisciplinary Care in Patients With Sotos Syndrome: A Single‐Center Experience

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Sotos syndrome is an autosomal dominant condition caused by pathogenic variants in the NSD1 gene on chromosome 5q35. It is characterized by macrosomia, distinctive facial features, and developmental delays. Patients are also reported to have a behavioral phenotype including autism spectrum disorder, attention deficit/hyperactivity disorder ...
Aravind Viswanathan   +4 more
wiley   +1 more source

The PRECiSE 2 trial of certolizumab pegol, a new PEGylated anti-TNF agent, in the treatment of Crohn's disease - An interview with David A Schwartz, 13 June 2007

open access: yesBiologics: Targets & Therapy, 2008
David A SchwartzVanderbilt University Medical Center, Nashville, TN, USAContext: Certolizumab pegol (CDP 870) is a new anti-tumor necrosis factor (TNF) therapy currently in development for the treatment of Crohn’s disease, rheumatoid arthritis,
David A Schwartz
doaj  

An International ASXL3 Natural History Study: Deep Phenotypic Analyses Including Detailed Reports of a Milder Phenotype, Novel Associations, and Clinical Recommendations

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Natural History Studies can help inform clinician and caregiver expectations, form the basis of management guidelines, and provide a comparator for therapeutic intervention. In rare conditions, where collection of prospective longitudinal data is untimely and impractical, quasi‐natural history data—from multiple individuals of different ages ...
E. Woods   +16 more
wiley   +1 more source

Enfermedad de Crohn con compromiso cutáneo mucoso Crohn disease with cutaneous mucosal involvement

open access: yesRevista Argentina de Dermatología, 2008
Comunicamos dos casos de enfermedad de Crohn con compromiso cutáneo-mucoso; el primer paciente con lesiones del denominado "Crohn metastásico" en las piernas y el segundo con importante compromiso en áreas perineo-genital, osteomal y de mucosa bucal, que
R E Achenbach   +3 more
doaj  

Mycobacterium avium subsp paratuberculosis and Crohn's disease [PDF]

open access: yes, 2008
Mycobacterium avium subsp paratuberculosis (MAP) é o agente etilógico da doença de Johne, uma doença inflamatória intestinal que afecta o gado, bem como outras espécies de mamíferos.
Assunção, Amélia Sarmento
core  

Smoking in inflammatory bowel diseases: Good, bad or ugly? [PDF]

open access: yes, 2007
Smoking is an important environmental factor in inflammatory bowel disease (IBD), having different effects in ulcerative colitis (UC) and Crohn’s disease (CD).
Lakatos, László   +2 more
core   +1 more source

Efficacy, Safety, Pharmacokinetics, and Immunogenicity of ABBV‐154 in Adults With Glucocorticoid‐Dependent Polymyalgia Rheumatica: A Phase 2, Randomized, Double‐Blind, Placebo‐Controlled Trial

open access: yesArthritis &Rheumatology, EarlyView.
Objective An unmet need exists for glucocorticoid‐sparing treatments for patients with polymyalgia rheumatica (PMR). The antibody‐drug conjugate ABBV‐154 comprises adalimumab conjugated to a glucocorticoid receptor modulator. We evaluated ABBV‐154 versus placebo in patients with glucocorticoid‐dependent PMR.
Robert F. Spiera   +14 more
wiley   +1 more source

Diagnosis of regional enrteritis (Crohn disease)

open access: yesThe Saudi Journal of Gastroenterology, 2003
Regional enteritis (Crohn disease) may present a diagnostic problem that needs to be solved by clinicians practicing in areas known to be endemic for tuberculosis.
Khalil Mohamed
doaj  

Inflammatory Bowel Disease-Experience of a pediatric gastroenterology unit [PDF]

open access: yes, 2013
Inflammatory bowel disease, especially Crohn disease, had increased in the last five decades. We analyzed all the patients of our unit diagnosed with the disease between 2001-2012 but we just considered the patients who respected the Porto criteria to ...
Antunes, Henedina, Nascimento, João
core   +1 more source

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