Results 91 to 100 of about 503,448 (361)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Contribution of Wheat Diversity to Total Factor Productivity in China
Journal of Agricultural and Resource Economics, 2008 The impact of wheat diversity on the productivity of wheat in China is examined using total factor productivity (TFP) and an instrumental variable approach.
Songqing Jin +4 more
doaj +1 more source
A participatory modeling method for multi-points of view description of a system from scientist's perceptions : application in seed systems modeling in Mali and Chile [PDF]
, 2011 This paper presents a participatory modeling for multi-points of view description of a system from scientists' knowledge. The method is applied in the development of a generic model for agro-biodiversity dynamics in developing countries with a focus on ...
Bazile, Didier +4 more
core
Insights into a long life without cancer: The case of the bowhead whale
Molecular Oncology, EarlyView.Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley +1 more source
Ecology and Society, 2016 We present a detailed ethnographic case study of sorghum seed acquisitions in a smallholder farming society in northern Cameroon. The effects of variability in household demographics and socioeconomic status on observed patterns of seed provisioning are ...
Jean Wencélius +3 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
BMC Research NotesObjective Plants control the direction of root growth toward moisture due to their sessile nature, a phenomenon known as hydrotropism. In Arabidopsis thaliana, the MIZU-KUSSEI1 (MIZ1) protein is essential for the hydrotropic response.
Su-Hwan Kwak, Wonkeun John Park
doaj +1 more source
THE DETERMINANTS OF CEREAL CROP DIVERSITY ON FARMS IN THE ETHIOPIAN HIGHLANDS [PDF]
On farm conservation of crop diversity entails policy challenges, especially when the diversity of crops maintained on farms has both inter-specific (among crops) and infra-specific (within a crop) components.
Benin, Samuel +4 more
core +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Weed management in cereals with cover crops - do they help of hinder? [PDF]
, 2018 Sustainable crop production calls for integrated weed management approaches. Cover crops (CCs) have been studied primarily in the context of soil fertility and soil structure but they might also supplement the weed management toolbox, particularly when ...
Salonen, Jukka
core