Results 91 to 100 of about 2,514,839 (304)

From acidity to sweetness: a comprehensive review of carbon accumulation in grape berries

Molecular Horticulture
Most of the carbon found in fruits at harvest is imported by the phloem. Imported carbon provide the material needed for the accumulation of sugars, organic acids, secondary compounds, in addition to the material needed for the synthesis of cell walls ...
Lizhen Lu, Serge Delrot, Zhenchang Liang
doaj   +1 more source

Outcrossing Levels and Fruit Quality in Single-Cultivar Blocks of a Multi-Cultivar Lychee (Litchi chinensis Sonn.) Orchard

Horticulturae
Intraspecific diversity is often introduced in orchards to promote cross-pollination, which is essential for self-incompatible crops and beneficial for many self-compatible crops.
Stephen J. Trueman, Joel Nichols
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

First Edition of Diversity Center Newsletter

, 2018
First Diversity Center newsletter, sent out at the beginning of 2018Documents and ...
UW Bothell Diversity Center
core  

Crop rotation phase has a greater impact on soil biology than crop rotation diversity

The effect of plant diversity on the belowground soil food web remains poorly understood. In this study the soil microbial community structure and biomass, and the abundance of microfauna, mesofauna, and macrofauna were assessed at three levels of crop ...
Thomas, Sion, Struijk, M., Leigh, Sam, Mortimer, Simon, Ashwood, F., Degani, Erika, Ashwood, Frank, Sizmur, Tom, Leigh, S. G., Whitmore, A. P., Thomas, S., Sizmur, T., Clark, Suzanne J., Mortimer, S. R., Bowen, Emma, Bowen, E., Struijk, Marijke, Degani, E., Whitmore, Andrew P., Clark, S. J.   +19 more
core   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Using Economics to Explain Spatial Diversity in a Wheat Crop: Examples from Australia and China [PDF]

Spatial diversity indicators may serve an important function for policymakers as they seek to manage crop genetic diversity and potential externalities associated with diffusion of some types of genetically improved crops.
Hu, Ruifa, Meng, Erika C.H., Brennan, John P., Smale, Melinda   +3 more
core  

Contribution of Wheat Diversity to Total Factor Productivity in China

Journal of Agricultural and Resource Economics, 2008
The impact of wheat diversity on the productivity of wheat in China is examined using total factor productivity (TFP) and an instrumental variable approach.
Songqing Jin, Erika C.H. Meng, Ruifa Hu, Scott Rozelle, Jikun Huang   +4 more
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source