Results 71 to 80 of about 2,514,839 (304)

Genetic erosion in crops: concept, research results and challenges [PDF]

open access: yes, 2010
The loss of variation in crops clue to the modernization of agriculture has been described as genetic erosion The current paper discusses the different views that exist on the concept of genetic erosion in crops Genetic erosion of cultivated diversity is
Visser, L.   +7 more
core   +1 more source

Dynamic transcriptomic features accompanying the onset of first flowering in roses

open access: yesBMC Plant Biology
Background Onset time of the first flowering is pivotal for the reproductive success of perennial polycarpic plants especially in woody species, like roses.
Jing Wen   +9 more
doaj   +1 more source

Accumulation of ph1 (zip4-5B) and ph2 (msh7-3D) mutations fails to boost homoeologous recombination in hexaploid wheat

open access: yesFrontiers in Plant Science
Diversification of the hexaploid (bread) wheat genetic pool using wild genetic resources relies on effective meiotic recombination (crossover) between wheat chromosomes and their counterparts from related species (homoeologues).
Camille Haquet   +9 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Long-term crop rotation diversification enhances maize drought resistance through soil organic matter

open access: yesEnvironmental Research Letters, 2021
Climate change adaptation requires building agricultural system resilience to warmer, drier climates. Increasing temporal plant diversity through crop rotation diversification increases yields of some crops under drought, but its potential to enhance ...
Leah L R Renwick   +6 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Crop diversity buffers the impact of droughts and high temperatures on food production

open access: yesEnvironmental Research Letters, 2023
Weather extremes like droughts and heat waves are becoming increasingly frequent worldwide, with severe consequences for agricultural production and food security.
Delphine Renard   +2 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Area And Diversity Of A Crop Reflects The Diversity Of Others

open access: yesJournal of Agriculture and Environment, 2013
This study was carried out to relate the diversity of one crop in terms of number of landraces and farm area with the diversity of other crop. Information collected during baseline survey of in-situ global project (1999) on three crops namely rice, finger millet and sponge gourd in Jumla, Kaski and Bara of Nepal were used. Farm area of each variety and
Devendra Gauchan   +3 more
openaire   +2 more sources

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

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