Results 101 to 110 of about 503,448 (361)

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Impact of Organic Crop and Livestock Systems on Earthworm Population Dynamics [PDF]

open access: yes, 2008
Earthworm population dynamics and diversity were evaluated in long-term farming systems experiments at the West Virginia University Organic Research Farm from 2000-2007.
Kotcon, Dr. James
core  

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Cross-Disciplinary Analysis of the On-Farm Transition from Conventional to Organic Vegetable Production [PDF]

open access: yes, 2008
This farm-scale analysis of the three-year transition to organic from conventional vegetable production tracked the changes in crop, soil, pest and management on two ranches (40 and 47 ha) in the Salinas Valley, California.
Jackson, Louise E.   +5 more
core  

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Uprooting Diversity? Peasant Farmers’ Market Engagements and the on-Farm Conservation of Crop Genetic Resources in the Guatemalan Highlands [PDF]

open access: yes
The long-term security of the global food supply is contingent upon the on-farm conservation of crop genetic diversity. Without it, food crops lack the ability to evolve in the face of new pests, emerging plant diseases, and changing environmental ...
S. Ryan Isakson
core  

Corn Interseeding Trial [PDF]

open access: yes, 2013
Growing a cover crop can enhance nutrient cycling and soil health while reducing soil erosion. However, getting cover crops established in corn silage systems has historically been problematic for Northeast growers due to the length of the growing season.
Burke, Conner   +4 more
core   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Demand and Supply of Crop Infraspecific Diversity on Farms: Towards a Policy Framework for On-Farm Conservation [PDF]

open access: yes
Interest is increasing worldwide in on-farm conservation as a component of a strategy to conserve crop genetic resources. On-farm conservation may require outside support to small-scale farmers in areas of crop domestication and diversity.
Bellon, Mauricio R.
core   +1 more source

Does crop diversity contribute to dietary diversity? Evidence from integration of vegetables into maize-based farming systems [PDF]

open access: yes, 2017
Background: Maize is the most important staple crop for food security and livelihood of smallholder farmers in many parts of sub-Saharan Africa, but it alone cannot ensure food security.
A Abdulai   +47 more
core   +2 more sources

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