Our shared global responsibility: Safeguarding crop diversity for future generations. [PDF]
Proc Natl Acad Sci U S A, 2023 Dempewolf H, Krishnan S, Guarino L.
europepmc +1 more source
Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region
FEBS Open Bio, EarlyView.Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson +2 more
wiley +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Data-driven approaches can harness crop diversity to address heterogeneous needs for breeding products. [PDF]
Proc Natl Acad Sci U S A, 2023 van Etten J +15 more
europepmc +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Journal of Agriculture and Rural Development in the Tropics and Subtropics, 2013 Households in much of the tropics depend for their livelihoods on the variety and continued production of food and other products that are provided by their own farms.
Tesfaye Abebe
doaj
The engineering of TBBPA-degrading synthetic microbiomes with integrated strategies
npj Biofilms and MicrobiomesThe capability to understand and construct synthetic microbiomes is crucial in biotechnological innovation and application. Tetrabromobisphenol A (TBBPA) is an emerging pollutant, and the understanding of its biodegradation is very limited.
Tong Wu +11 more
doaj +1 more source
Crop diversity and susceptibility of crop fields to elephant raids in eastern Okavango Panhandle, northern Botswana. [PDF]
Ecol Evol, 2023 Matsika TA +7 more
europepmc +1 more source
FEBS Open Bio, EarlyView.We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
A 14-3-3 modulator of seed weight and quality for unlocking the yield potential of soybean
Nature CommunicationsSeed weight is a key component of crop yield. However, molecular mechanisms underlying soybean seed weight variation remain largely elusive. Here, we identify a major seed weight determining gene Glycine max SMALL SEED 6 (GmSMS6) that encodes a 14-3-3 ...
Bingbing Li +9 more
doaj +1 more source