PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
The engineering of TBBPA-degrading synthetic microbiomes with integrated strategies
npj Biofilms and MicrobiomesThe capability to understand and construct synthetic microbiomes is crucial in biotechnological innovation and application. Tetrabromobisphenol A (TBBPA) is an emerging pollutant, and the understanding of its biodegradation is very limited.
Tong Wu +11 more
doaj +1 more source
Optimizing crop diversity across multiple spatial scales
Environmental and Sustainability IndicatorsIncreasing crop diversity in agricultural landscapes can increase biodiversity but it is unclear how different diversification strategies affect crop diversity across spatial scales. Here we compared different diversification strategies for farmers along
T.P.M. van Loon +2 more
doaj +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Journal of Agriculture and Rural Development in the Tropics and Subtropics, 2013 Households in much of the tropics depend for their livelihoods on the variety and continued production of food and other products that are provided by their own farms.
Tesfaye Abebe
doaj
A 14-3-3 modulator of seed weight and quality for unlocking the yield potential of soybean
Nature CommunicationsSeed weight is a key component of crop yield. However, molecular mechanisms underlying soybean seed weight variation remain largely elusive. Here, we identify a major seed weight determining gene Glycine max SMALL SEED 6 (GmSMS6) that encodes a 14-3-3 ...
Bingbing Li +9 more
doaj +1 more source
Data-driven approaches can harness crop diversity to address heterogeneous needs for breeding products. [PDF]
Proc Natl Acad Sci U S A, 2023 van Etten J +15 more
europepmc +1 more source
Role of crop residue mulches and their decomposition on soil functions in conservation agriculture : S11.03a -6 [PDF]
, 2012 Core principle of Conservation Agriculture is to maintain soil cover by crop residue mulching or cover crops. Mulching practice affects many agroecosystem services, through water dynamics and C and N transformations (Coppens et al., 2007) and their ...
Akhtar, Iqbal +7 more
core
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Crop diversity and susceptibility of crop fields to elephant raids in eastern Okavango Panhandle, northern Botswana. [PDF]
Ecol Evol, 2023 Matsika TA +7 more
europepmc +1 more source