Results 121 to 130 of about 709,594 (295)

M-Cube — towards correlative multi-scale light-sheet imaging using a compact, modular and moving illuminator [PDF]

open access: yesEPJ Web of Conferences
The crossed arrangement of excitation and collection optics is the defining feature of selective plane illumination microscopes. It results in an axial sectioning given by the thickness of the light sheet, whereas the lateral resolution depends on the ...
Touja Hugo   +4 more
doaj   +1 more source

Hopf crossed module (co)algebras [PDF]

open access: yes
Given a crossed module $\chi$, we introduce Hopf $\chi$-(co)algebras which generalize Hopf algebras and Hopf group-(co)algebras. We interpret them as Hopf algebras in some symmetric monoidal category. We prove that their categories of representations are
Sozer, Kursat, Virelizier, Alexis
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Higher Dimensional Leibniz-Rinehart Algebras

open access: yesJournal of Mathematical Sciences and Modelling
In this article, we delve into the realm of higher dimensional Leibniz-Rinehart algebras, exploring the intricate structures of Leibniz algebroids and their applications.
Mahmut Koçak, Selim Çetin
doaj   +1 more source

Modules over Crossed Products

open access: yesJournal of Algebra, 1999
Let \(R\) be either a division ring or a left Noetherian simple ring of Krull dimension 1. Suppose that \(G\) is a supersolvable group and \(C=R*G\) a crossed product. Assume that \(C\) is a simple right Ore domain. Then any left ideal of \(C\) is stably 2-generated, any left stably free module of rank \(\geq 2\) is free.
openaire   +2 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Homotopy of lie-rinehart crossed module morphisms

open access: yes, 2019
Bu makalede amacımız Lie-Rinehart çapraz modüllerin morfizmlerinin homotopi kavramını vermektir. Homotopi bağıntısı bir denklik bağıntısı oluşturduğunu, buna ek olarak Lie- rinehart çapraz modül morfizmleri ve homotopileri bir groupoid yapısı olduğunu ...
Çetin, Selim, Çobankaya, Ayşe
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Baer Invariants of Crossed Modules

open access: yesJournal of Algebra, 1993
The author translates into the language of categories of (pre)crossed modules some results on Baer invariants of groups. This creates a unified procedure for viewing some previously known results, e.g., those by \textit{D. Conduché} and \textit{G. J. Ellis} [Quelques propriétés homologiques des modules précroisés, J. Algebra 123, No.
openaire   +2 more sources

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

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