Results 81 to 90 of about 364,075 (332)

Genetic Crosses and Linkage Mapping in Schistosome Parasites [PDF]

open access: yesTrends in Parasitology, 2018
Linkage mapping - utilizing experimental genetic crosses to examine cosegregation of phenotypic traits with genetic markers - is now 100 years old. Schistosome parasites are exquisitely well suited to linkage mapping approaches because genetic crosses can be conducted in the laboratory, thousands of progeny are produced, and elegant experimental work ...
Tim J. Anderson   +3 more
openaire   +3 more sources

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Evaluation of early generation progenies, (F2) of fenugreek (Trigonella foenum-graecum L.) crosses for seed yield and yield related characters [PDF]

open access: yes, 2003
F2 generation of five crosses of fenugreek were evaluated for seed yield and its components along with parents. F2 generation had wider range than the parents for most of the characters in the crosses.
Singh, R S Raje, D L Singhania, D
core   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Optimized breeding strategies to harness genetic resources with different performance levels

open access: yesBMC Genomics, 2020
Background The narrow genetic base of elite germplasm compromises long-term genetic gain and increases the vulnerability to biotic and abiotic stresses in unpredictable environmental conditions. Therefore, an efficient strategy is required to broaden the
Antoine Allier   +4 more
doaj   +1 more source

On genetic correlation estimation with summary statistics from genome-wide association studies [PDF]

open access: yesarXiv, 2019
Genome-wide association studies (GWAS) have been widely used to examine the association between single nucleotide polymorphisms (SNPs) and complex traits, where both the sample size n and the number of SNPs p can be very large. Recently, cross-trait polygenic risk score (PRS) method has gained extremely popular for assessing genetic correlation of ...
arxiv  

Frequency of superior yielding segregates from soybean crosses ranked on the basis of best linear unbiased predictions of parents [PDF]

open access: yes, 1997
Plant breeding can be improved by methods that give reliable predictions of crosses which produce the highest frequencies of segregates which are higher yielding than existing genotypes.
Johnson, Richard DeWayne
core   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

Demonstration of a genetic-algorithm-optimized cavity-based waveguide crossing [PDF]

open access: yesarXiv, 2017
A compact, single-etch silicon photonics waveguide crossing based on low quality factor cavity and optimized by a genetic algorithm is demonstrated. The device has 0.1~0.3 dB insertion loss and < -35 dB crosstalk per crossing for fundamental TE mode in the 1550-1600 nm wavelength band, with a footprint of 5 x 5 {\mu}m$^2$.
arxiv  

Genetic Dissection of Cytonuclear Epistasis in Line Crosses [PDF]

open access: yesGenetics, 2007
Abstract Dissection of cytonuclear interactions is fundamentally important for understanding the genetic architecture of complex traits. Here we propose a mating design based on reciprocal crosses and extend the existing QTL mapping method to evaluate the contribution of cytoplasm and QTL × cytoplasm interactions to the phenotypic ...
Zefeng Yang   +4 more
openaire   +3 more sources

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