Results 51 to 60 of about 376,834 (244)

Enzymatic Cross-Linking of Dynamic Thiol-Norbornene Click Hydrogels [PDF]

, 2019
Enzyme-mediated in situ forming hydrogels are attractive for many biomedical applications because gelation afforded by enzymatic reactions can be readily controlled not only by tuning macromer compositions, but also by adjusting enzyme kinetics.
Hudson, Britney N., Lin, Chien-Chi, Liu, Hung-Yi, Nguyen, Han D.   +3 more
core   +2 more sources

Keratoconus: A biomechanical perspective on loss of corneal stiffness

Indian Journal of Ophthalmology, 2013
Keratoconus (KC) is progressive disease of corneal thinning, steepening and collagen degradation. Biomechanics of the cornea is maintained by the intricate collagen network, which is responsible for its unique shape and function.
Abhijit Sinha Roy, Rohit Shetty, Mathew Kurian Kummelil   +2 more
doaj   +1 more source

Crosslinking method of hyaluronic-based hydrogel for biomedical applications

Journal of Tissue Engineering, 2017
In the field of tissue engineering, there is a need for advancement beyond conventional scaffolds and preformed hydrogels. Injectable hydrogels have gained wider admiration among researchers as they can be used in minimally invasive surgical procedures ...
Sureerat Khunmanee, Younghyen Jeong, Hansoo Park   +2 more
semanticscholar   +1 more source

The histone chaperones Nap1 and Vps75 bind histones H3 and H4 in a tetrameric conformation [PDF]

, 2011
Histone chaperones physically interact with histones to direct proper assembly and disassembly of nucleosomes regulating diverse nuclear processes such as DNA replication, promoter remodeling, transcription elongation, DNA damage, and histone variant ...
Bowman, A., El-Mkami, Hassane, Norman, David George, Owen-Hughes, Tom, Singh, Vijender, Ward, Richard, Wiechens, Nicola   +6 more
core   +4 more sources

Assessment of the characteristics and biocompatibility of gelatin sponge scaffolds prepared by various crosslinking methods

Scientific Reports, 2018
This comparative study aims to identify a biocompatible and effective crosslinker for preparing gelatin sponges. Glutaraldehyde (GTA), genipin (GP), 1-ethyl-3-(3-dimethyl aminopropyl)carbodiimide (EDC), and microbial transglutaminase (mTG) were used as ...
Gang Yang, Zheng-hua Xiao, Haiyan Long, Kunlong Ma, Junpeng Zhang, Xiaomei Ren, Jiang Zhang   +6 more
semanticscholar   +1 more source

A synthetic peptide library for benchmarking crosslinking-mass spectrometry search engines for proteins and protein complexes

Nature Communications, 2020
Crosslinking-mass spectrometry (XL-MS) serves to identify interaction sites between proteins. Numerous search engines for crosslink identification exist, but lack of ground truth samples containing known crosslinks has precluded their systematic ...
R. Beveridge, J. Stadlmann, J. Penninger, K. Mechtler   +3 more
semanticscholar   +1 more source

Exploring Extracellular Matrix Crosslinking as a Therapeutic Approach to Fibrosis

Cells
The extracellular matrix (ECM) provides structural support for tissues and regulatory signals for resident cells. ECM requires a careful balance between protein accumulation and degradation for homeostasis.
Sarah M. Lloyd, Yupeng He
doaj   +1 more source

Ion exchange membranes based upon crosslinked sulfonated polyethersulfone for electrochemical applications [PDF]

, 2013
Synthesis and characterization of new ion exchange membranes made from chlorosulfonated polyethersul- fone (SO2Cl-PES) crosslinked by polyaminated crosslinking reagents have been performed.
FAUVARQUE, J.F, MABROUK, Walid, MATOUSSI, F., OGIER, Lionel, SOLLOGOUB, Cyrille, VIDAL, Serge   +5 more
core   +5 more sources

Computational and Experimental Characterization of Aligned Collagen across Varied Crosslinking Degrees

Micromachines
Collagen-based scaffolds have been widely used in tissue engineering. The alignment of collagen fibers and the degree of crosslinking in engineering tissue scaffolds significantly affect cell activity and scaffold stability.
Shengmao Lin, Nashaita Y. Patrawalla, Yingnan Zhai, Pengfei Dong, Vipuil Kishore, Linxia Gu   +5 more
doaj   +1 more source

Suitability of EGCG as a Means of Stabilizing a Porcine Osteochondral Xenograft

Journal of Functional Biomaterials, 2017
As a non-crosslinked osteochondral xenograft would be mechanically inferior to native cartilage and vulnerable to premature degradation, we seek a safe and effective method of xenograft stabilization.
Steven Elder, John Clune, Jaylyn Walker, Paul Gloth   +3 more
doaj   +1 more source