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Neutralization of crotalid venoms by fractions from snake sera

Toxicon, 1978
Abstract Neutralization of crotalid venoms by fractions from snake sera. Toxicon16, 603–609, 1978.—A protein fraction is present in the sera of snakes belonging to Crotalidae and Colubridae. which protects mice from the lethal effect of 5 ld 50 of crotalid venoms injected i.p. When the sera were subjected to ammonium sulfate fractionation, the 0–45%
B, Philpot   +4 more
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Isolation and characterization of myotoxic phospholipases A2 from crotalid venoms

Toxicon, 1986
Phospholipases A2 producing myonecrosis when injected i.m. into mice were isolated from venoms of Trimeresurus flavoviridis, Agkistrodon bilineatus, A. c. contortrix, A. c. mokeson, A. p. piscivorus and Bothrops asper by gels filtration on Sephadex G-75 followed by ion-exchange chromatography on CM-cellulose.
D, Mebs, Y, Samejima
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Some Effects of Heat-Labile Venom Components on Indirect Hemolysis by Crotalid Venoms

The American Journal of Tropical Medicine and Hygiene, 1970
Abstract The hemolytic activities of the venom of Agkistrodon contortrix mokeson, Agkistrodon piscivorus leucostoma, Crotalus atrox, and Crotalus scutulatus were studied by using hypotonic solutions. The effects with whole venoms plus lecithin were compared with effects caused by boiled venom supernatant fluids containing phospholipase A and lecithin ...
F E, Byrd, B D, Johnson
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Antigenic relationships between Mojave toxin subunits, Mojave toxin and some crotalid venoms

Toxicon, 1986
Immunochemical responses of a number of pit viper venoms to antibodies derived separately from the acidic and basic subunits were investigated by enzyme linked immunosorbent assay (ELISA) and Ouchterlony immunodiffusion. The polyclonal antisera to the basic subunit were generated in rabbits, whereas mouse hybridoma cell cultures were used to produce ...
J T, Henderson, A L, Bieber
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Antibacterial Activity of Crotalid Venoms against Oral Snake Flora and Other Clinical Bacteria

Journal of Infectious Diseases, 1991
Despite heavy oral and fang contamination of crotalid species with a wide variety of potentially pathogenic bacteria, crotalid envenomation is associated with a low incidence of bacterial infection. Minimal inhibitory and bactericidal concentrations of venoms from three crotalid species were determined against six aerobic and eight anaerobic reference ...
D A, Talan   +5 more
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Neutralization of kinin-releasing enzymes of crotalid venoms by monospecific and polyspecific antivenoms

Toxicon, 1991
The amounts of kinin-releasing enzymes in the venoms of Crotalus atrox, Crotalus adamanteus, Crotalus scutulatus scutulatus and Agkistrodon piscivorus piscivorus were measured by determining the amounts of kinin released from a sheep kininogen substrate by means of a specific radioimmunoassay. Four monospecific and two commercial polyspecific antivenom
G S, Bailey   +3 more
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Inhibition of the myotoxic and hemorrhagic activities of crotalid venoms by Eclipta prostrata (Asteraceae) extracts and constituents

Toxicon, 1994
The antimyotoxic and antihemorrhagic effects of Eclipta prostrata (EP) and three of its constituents (wedelolactone, WE; stigmaterol, ST; and sitosterol, SI) were investigated. The myotoxicity of crotalid venoms (Bothrops jararaca, Bothrops jararacussu and Lachesis muta), purified myotoxins (bothropstoxin, BthTX; bothropasin; and crotoxin), and ...
P A, Melo   +3 more
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Affinity-Purified, Mixed Monospecific Crotalid Antivenom Ovine Fab for the Treatment of Crotalid Venom Poisoning

Annals of Emergency Medicine, 1997
To test the efficacy and safety of a new antivenom, affinity-purified, mixed monospecific crotalid antivenom ovine Fab, in human subjects with minimal or moderate crotalid envenomation.We conducted a prospective multicenter clinical trial of 11 patients 10 years or older with progressive manifestations after mild to moderate crotalid snakebite.
R C, Dart   +8 more
openaire   +2 more sources

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